Association between level of HbA1c and lipid profile in T2DM patients attending diabetic OPD at BPKIHS (original) (raw)

Hyperglycemia, dyslipidemia and coronary artery disease relate well with each other in type 2 diabetes and it has been proposed that higher prevalence of cardiovascular disease in type 2 diabetes is due to chronic uncontrolled hyperglycemia. Our study aimed to find utility of Hba1c as indicator of dyslipidemia in patients with type 2 diabetes mellitus. We enrolled 168 T2DM patients in our study and collected venous blood samples in both plain and EDTA vials after a fast of minimum 8 hours. Biochemical analysis was done in fully automated analyzer cobas c311. HbA1c was found to have significant positive correlation with total cholesterol, LDL-C, and triglyceride and significant negative correlation with HDL-C and HDL/LDL ratio. The mean value of TC, LDL-C and TG was found to be lower in patients with good glycemic control than those with poor glycemic control. But, mean value of HDL and HDL/LDL ratios were found to be higher in patients with good glycemic control than those with poor glycemic control. These differences were significant at the level of p <0.05. Our study suggests additional use of HbA1c as indicator of dyslipidemia.