Risk factors associated with congenital anomalies among newborns in southwestern Ethiopia: A case-control study (original) (raw)

PLoS ONE, 2021

Abstract

Introduction Human embryo is well protected in the uterus by the embryonic membrane, although teratogens may cause developmental disruptions after maternal exposure to them during early pregnancy. Most of the risk factors contributing to the development of congenital anomalies are uncertain; however, genetic factors, environmental factors and multifactorial inheritance are found to be risk factors. Regardless of their clinical importance, there are little/no studies conducted directly related to predisposing risk factors in southwestern Ethiopia. Objective The study aimed to determine the associated risk factors with congenital anomalies among newborns in southwestern Ethiopia. Methods Case—control study was conducted on newborns and their mothers in six purposively selected hospitals in southwestern Ethiopia from May 2016 to May 2018. Data was collected after evaluation of the neonates for the presence of congenital anomalies using the standard pretested checklist. The data was ana...

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