Diabetes and Metabolic Syndrome Disorders (original) (raw)
2015
Abstract
Type 2 Diabetes Mellitus (DM) could be associated with cognitive impairment. The spectrum of cognitive impairment ranges from mild deficits that are not clinically detectable to the most severe clinical form, dementia. Some of the potential mechanisms include the effects of brain infarcts, white matter disease, hyperinsulinaemia, advanced glycosylated end products, and Lipoprotein Related Proteins (LRP). There is limited data on the prevalence of cognitive impairment amongst type 2 DM patients in south - east Nigeria. Therefore, this study was undertaken to determine the prevalence of cognitive impairment in type 2 DM patients attending a diabetic clinic in Abakaliki south-east Nigeria. It is a cross-sectional, descriptive and hospital based study carried out over a three months period (October 2013 to September 2014). Mini Mental State Examination (MMSE) was used for cognitive functions assessment and interpreted as follows; a score of 25-30 as normal, and ≤24 as cognitive impairme...
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