Polarity effect of microcurrent electrical stimulation on tendon healing: Biomechanical and histopathological studies. (original) (raw)
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The pulsed and static magnetic field were used in treatment of tenectomy achilles tendon, which no significant results at level of P 0.05 in both groups. Eighteen rabbits were used in present study, the animals were divided into three equal groups , 1 st group was treated with pulsed magnetic field (650 Gauss,50 Hz), 2 nd group was treated with static magnetic field (650 Gauss), while 3 rd group was used as a control group. The magnetic therapy was continued to four weeks post surgery/ twice daily. Clinical signs were recorded to all groups, loading force and jumbling power tests which used in athletics to knowledge achilles tendon sufficiency post surgery. The magnetic treated groups were showed significant result with control group at P 0.05, while no significant results at P 0.05 between pulsed and static groups. Blood parameters were examined, there significant result at between magnetic groups and control group at P 0.05 during the 1 st-four weeks (treatment period), while return to unsignificant at seven weeks post surgery at P 0.05. The gross and histopathological picture were taken at seven post surgery, semi complete healing in magnetic groups, while control group was showed more collagen and fibroblast. In conclusions of this study, the magnetic field therapy have ability to acceleration healing the rupture tendon increase blood parameters. Theorically, the mechanism of action magnetic field to accelerate healing was discussed.
Modulation of tendon fibroplasia by exogenous electric currents
Bioelectromagnetics, 1988
A chicken tendon explant model system has been developed to investigate the effects of extremely-low-frequency (ELF), low-amplitude, unipolar, square wave pulsed electric fields on fibroplasia in vitro. An electric field parameter set consisting of l-Hz, l-ms duration pulses, with a time-averaged current density of 7 mA/m2 (peak current density 7 A/m2) induced maximal (32 %) increase in fibroblast proliferation in tendon explants exposed for 4 days. Exposure to the same field at an average current density of 1.8 mA/ m2 had no effect on fibroblast proliferation, whereas exposure to current densities on > 10 mA/m2 inhibited proliferation and relative collagen synthesis, without affecting noncollagen protein synthesis. Fibroplasia was significantly increased in explants oriented parallel to applied electric fields having current densities of 3.5 or 7 mA/m2, but there was no detectable effect on explants oriented perpendicular to the same electric field. Fibroblast proliferation and relative collagen synthesis were inversely proportional to donor age for chickens in the 3-to 16-week age group used in this study. For these dependent variables (proliferation and relative collagen synthesis), there was no interaction between donor age and ELF electric field exposure.
Pulsed electromagnetic fields improve the healing process of Achilles tendinopathy
Bone & Joint Research, 2020
Aims In the context of tendon degenerative disorders, the need for innovative conservative treatments that can improve the intrinsic healing potential of tendon tissue is progressively increasing. In this study, the role of pulsed electromagnetic fields (PEMFs) in improving the tendon healing process was evaluated in a rat model of collagenase-induced Achilles tendinopathy. Methods A total of 68 Sprague Dawley rats received a single injection of type I collagenase in Achilles tendons to induce the tendinopathy and then were daily exposed to PEMFs (1.5 mT and 75 Hz) for up to 14 days - starting 1, 7, or 15 days after the injection - to identify the best treatment option with respect to the phase of the disease. Then, 7 and 14 days of PEMF exposure were compared to identify the most effective protocol. Results The daily exposure to PEMFs generally provided an improvement in the fibre organization, a decrease in cell density, vascularity, and fat deposition, and a restoration of the ph...
Bioelectricity and microcurrent therapy for tissue healing – a narrative review
Physical Therapy Reviews, 2009
Microcurrent therapy is unique amongst the electrophysical modalities in applying electric fields and currents of similar form and magnitude to those produced naturally by the body. The therapy involves application of electric currents of the order of millionths of an amp, and there is evidence that it can promote healing in a variety of damaged tissues. Clinical trial evidence indicates that the therapy may be effective with non-uniting fractures, spinal fusions and a skin ulcers of varying aetiology, particularly where other forms of treatment have not been successful. In vitro, animal and human studies also suggest that there is unexplored potential for the application of microcurrent to a variety of musculoskeletal disorders. However, higher quality and more comprehensive clinical trial data may be required before musculoskeletal clinicians consider adding this modality to their electrotherapy repertoire.
Low Frequency Ultrasonic Versus Microcurrent Effect on Tissue Healing After Tendon Suture
2014
Background: Tendon injury has poor healing process. Therapeutic US has a positive role to play in providing the growth factors, also Microcurrent therapy has been used to increase the rate of healing. Purpose: this study was conducted to investigate the difference between high frequency ultrasound versus microcurrent therapy on the tissue healing of Achilles tendon after suture. Methods: Thirty female albino rats were surgically transected Achilles tendons, were randomly and assigned into three groups with ten rats in each group (group I served as a control, group II was treated with high frequency US and group III was treated with microcurrent). The treatments were administered with ultrasound and microcurrent day other day starting immediately from the day after injury for 5 weeks. Wound size measurements were evaluated till complete healing. Results: Both low frequency ultrasonic and microcurrent have a significant effect on decreasing wound size where the mean value of the wound...
American Journal of Veterinary Research, 2006
Objective—To determine the relationship between the output of an electrical treatment device and the effective field strength in the superficial digital flexor tendon of horses. Sample Population—Cadaver horse forelimbs without visible defects (n = 8) and 1 live pony. Procedure—Microcurrents were generated by a microcurrent electrical therapy device and applied in proximodistal, dorsopalmar, and mediolateral directions in the entire forelimbs, dissected tendons, and the pony with various output settings. Corresponding field strengths in the tendons were measured. Results—A linear relationship was detected between current and field strength in all conditions and in all 3 directions. In dissected tendons, significant differences were detected among all 3 directions, with highest field strength in the proximodistal direction and lowest in the dorsopalmar direction. In the entire forelimbs, field strength in the proximodistal direction was significantly lower than in the mediolateral di...
Intrasound therapy in tendon healing: is intensity a factor?
Open Access Rheumatology: Research and Reviews, 2010
This study investigated the effects of low-and high-intensity intrasound therapy (LITR and HITR, respectively) given once daily and twice daily on the morphology and oxidative stress in healing tendon tissue following an acute injury. Methods: Eighty-five male rats, randomized into six groups were further subdivided into groups A, B, and C, except for Group 1 which was subdivided into A and B only. Groups 2-6 underwent an induced crush injury. The six groups were allocated to: serve as controls (Group 1), receive no treatment (Group 2), HITR twice daily (Group 3), HITR once daily (Group 4), LITR twice daily (Group 5), and LITR once daily (Group 6). Intrasound therapy (ITR) was commenced 24 hours postinjury and was given once daily or twice daily over the first 14 days postinjury. The animals in subgroups A and B were sacrificed on day 15 postinjury, and those in subgroup C were sacrificed on day 31 postinjury. The tendons were excised, and processed for histology and malondialdehyde (MDA) assay. Results: There was no significant difference in the tenocyte population between the HITR-and LITR-treated groups. However, twice-daily treatment in either the low-or high-intensity mode resulted in significant tenocyte proliferation compared with the once-daily treated groups, and also had the highest percentage of tenoblasts compared with the population of tenocytes in the proliferative phase of healing. All treatment protocols marginally lowered the MDA level. Conclusion: The role of IRT in tendon healing is influenced more by the frequency of treatment rather than the intensity of the delivered dosage.
Pulsed Magnetic Field Therapy Increases Tensile Strength in a Rat Achilles’ Tendon Repair Model
Journal of Hand Surgery-american Volume, 2006
To examine the effect of pulsing electromagnetic fields on the biomechanic strength of rat Achilles' tendons at 3 weeks after transection and repair. Methods: This noninvasive modality was tested in a prospective, randomized, doubleblinded, placebo-controlled study to evaluate the effect of a specific noninvasive radiofrequency pulsed electromagnetic field signal on tendon tensile strength at 21 days post transection in a rat model. Results: In the animals receiving PMF exposure, an increase in tensile strength of up to 69% was noted at the repair site of the rat Achilles' tendon at 3 weeks after transection and repair compared with nonstimulated control animals.
Brain Research, 2010
Electrical stimulation of the Achilles tendon (TES) produced strong reflex depression (duration > 250 ms) of a small background contraction in both heads of gastrocnemius (GA) via large diameter electrodes localized to the tendon. The inhibitory responses were produced without electrical (M wave) or mechanical (muscle twitch) signs of direct muscle stimulation. In this study, the contribution of presynaptic and postsynaptic mechanisms to the depression was investigated by studying conditioning effects of tendon afferent stimulation on the mechanical tendon reflex (TR) and magnetic motor evoked potential (MEP). TES completely inhibited the TR over an ISI of 300 ms that commenced before and continued during and after the period of voluntary EMG depression. Tendon afferent conditioning stimuli also partially inhibited the MEP, but over a short time course confined to the period of voluntary EMG depression. The strength and extended time course of tendon afferent conditioning of the TR and its failure to produce a similar depression of the MEP are consistent with a mechanism involving presynaptic inhibition of Ia terminals. Cutaneous (sural nerve) afferent conditioning partially inhibited the TR and MEP over a short time course (ISI < 100 ms) resembling the inhibition seen in the voluntary EMG. This was consistent with the postsynaptic origin of cutaneous inhibition of the motoneurons.