Adenomatoid Tumour of the Uterus: A Rare Case Report (original) (raw)
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Adenomatoid tumor of the uterus; report of a rare incidentaloma
International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2014
Adenomatoid tumor of the uterus is extremely rare and usually an incidental finding in the uteri removed surgically for some other cause as in the present case. The histogenesis of this tumor has been controversial ever since its discovery, although the most favored and proposed is a mesothelial origin. Grossly it is usually mistaken for a leiomyoma. The tumor may have a variety of histomorphologic patterns with rare bizarre appearances, at times leading to an erroneous diagnosis of metastatic adenocarcinoma.
Objective Adenomatoid tumor is a benign neoplasm of mesothelial origin encountered most often in the male and female genital tracts. This tumor has a distinct morphology and is characterized by anastomosing and variably sized tubules lined by epithelioid and flattened cells. Only 4 cases of the extremely rare leiomyoadenomatoid variant are on record. We report 5 cases of adenomatoid tumor including 3 cases of leiomyoadenomatoid tumor of the uterus, which is an extremely rare variant of adenomatoid tumor, difficult to recognize on morphology.
Open Journal of Obstetrics and Gynecology, 2013
Genital origin adenocarcinomas with coexisting uterine adenomatoid tumors are very rare with only four published cases in the literature. We report a case of adenomatoid tumor of the uterus that was found incidentally during treatment of cervical adenocarcinoma. Although adenomatoid tumors may cause a differential diagnostic problem, in our case the hematoxylin-eosin histological and immunhistochemical studies confirmed mesothelial phenotype of tumor and these also helped in differentiating an adenomatoid tumor from the carcinomatous myometrial invasion. Adenomatoid tumors are easily recognizable benign pathologies. An incidental finding of adenomatoid tumors accompanied by adenocarcinoma of the endometrium or cervix should always be considered.
Leiomyoadenomatoid tumor of uterus: two case reports with literature review
Surgical and Experimental Pathology
Background Adenomatoid tumors (AT) are benign neoplasms of mesothelial origin that occur more frequently in the genital tracts. In uterus, AT are usually located in the subserosa of the cornual myometrium. Microscopically, it is characterized by interanastomosing pseudoglands or pseudovascular spaces and striking smooth-muscle hypertrophy is often present. In some cases, the prominence of smooth muscle component simulates a leiomyoma and the lesion is denoted as a leiomyoadenomatoid tumor. The microscopic appearance of the adenomatoid component (AC) may mimic a malignant tumor due to irregular pseudoinfiltration with tubular formations. Just 16 cases with this morphological presentation were found in the literature review. Case presentations The first case, a 38-year-old female, showed lower abdominal pain, menorrhagia, postcoital bleeding and previous history of uterin leiomyoma. The second case, a 26-year-old female, had clinical complaint of metrorrhagia and received diagnostic h...
Multifocal adenomatoid tumor of myometrium: A case report and review of literature
A case of multifocal adenomatoid tumors (mAT) of the myometrium is presented. The patient, a 49-year-old woman underwent vaginal hysterectomy for severe pelvic pain renitent to medical therapy. Diagnosis was made based on histologic examination and immunohistochemistry (IHC). AT should be considered in the differential diagnosis with leiomyoma in patients with severe pelvic pain and an enlarged uterus due to multiple nodules.
Uterine Adenosarcoma: A Case Report and Review of Literature
Journal of Obstetrics, Gynecology and Cancer Research, 2022
Uterine adenosarcoma (UA) is an infrequent malignancy which contains the epithelium of benign glands and malignant mesenchymal elements. Low-grade adenosarcoma has a sarcomatous part that is uniformly low grade. Uterine adenosarcoma includes 8% of all uterine sarcomas and less than 0.2% of uterine neoplasms. It is more common in perimenopausal or postmenopausal women. Due to the rarity of uterine adenosarcoma, limited information is available to help guide treatment. A 33-year-old woman, who had one child referred to Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, (Tehran, Iran), with a complaint of abnormal uterine bleeding for one year; the sonography reported a polyp in fundal cavity of uterus. The patient underwent hysteroscopy and curettage. The pathology examination revealed uterine adenosarcoma which led to a total hysterectomy and bilateral salpingo-oophorectomy. Abnormal uterine bleeding is the most common symptom of UA. At a young age there is a possibility of misdiagnosis. Hysteroscopy should also be performed if symptomatic or enlarge polypoid lesions are diagnosed preoperatively.
Uterine Adenosarcoma: About Two Cases
The International Annals of Medicine, 2017
Uterine adenosarcoma is a rare tumor (8% of uterine sarcomas) with a dual component: a benign proliferative epithelium and a sarcomatous stroma. The objective of this work is to report the clinical aspects and therapeutic modalities of two cases of uterine adenosarcoma. The risk factors are unknown; its clinical symptomatology is polymorphic dominated by metrorrhagia. A total hysterectomy with bilateral adnexectomy is satisfaction as treatment. Its prognosis is relatively favorable.
Uterine adenomyosis: a need for uniform terminology and consensus classification
Reproductive Biomedicine Online, 2008
Modern imaging techniques allow non-invasive diagnosis of adenomyosis, a relatively common disorder characterized by the presence of heterotopic endometrial glands and stroma in the myometrium with hyperplasia of the adjacent smooth muscle. The study of adenomyosis is greatly hampered by a lack of clear terminology and the absence of a consensus classification of the lesions. Any classification of adenomyosis must
Adenoma malignum of the uterine cervix: report of four cases
World Journal of Surgical Oncology, 2013
Adenoma malignum (AM) of the cervix is a rare disease and it is difficult to diagnose due to the deceptively benign appearance of the tumor cells. These lesions have mucin-rich cystic lesions and are usually situated deep in the cervix. Since AM is very rare, standard screening tests, diagnostic tools and treatments have not yet been established. Radiologically, it mimics multiple nabothian cysts as a benign-looking tumor. Histologically, AM is a well-differentiated adenocarcinoma and could be misdiagnosed as a benign lesion. These findings make a preoperative diagnosis of AM difficult and can result in surgery being performed based on a misdiagnosis. We report here on four cases of pathologically confirmed AM.