Oxypurinol as an inhibitor of xanthine oxidase-catalyzed production of superoxide radical (original) (raw)
Superoxide radical production by allopurinol and xanthine oxidase
Chiara Galbusera, David Fedida
Biochemical Pharmacology, 2006
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Changes in xanthine oxidase in ischemic rat brain
Masatsune Ishikawa
Journal of Neurosurgery, 1989
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Role of xanthine oxidase inhibitor as free radical scavenger: A novel mechanism of action of allopurinol and oxypurinol in myocardial salvage
dk das
Biochemical and Biophysical Research Communications, 1987
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Oxypurinol, a xanthine oxidase inhibitor and a superoxide scavenger, did not attenuate ischemic neuronal damage in gerbils
Toshiyuki Arai
Life Sciences, 1998
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Physiologic Levels of Uric Acid Inhibit Xanthine Oxidase in Human Plasma
Arnold Rivera
Pediatric Research, 1993
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Relationship between plasma oxipurinol concentrations and xanthine oxidase activity in volunteers dosed with allopurinol
Richard Day
British Journal of Clinical Pharmacology, 1988
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Deleterious effects of xanthine oxidase on rat liver endothelial cells after ischemia/reperfusion
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Therapeutics and Clinical Risk Management, 2009
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The xanthine oxidase inhibitor oxypurinol does not limit infarct size in a canine model of 40 minutes of ischemia with reperfusion
Robert Jennings
Journal of the American College of Cardiology, 1988
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Allopurinol and oxypurinol are hydroxyl radical scavengers
Martin Grootveld
FEBS Letters, 1987
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Improved survival in intestinal ischemia by allopurinol not related to xanthine-oxidase inhibition
Juan Nuñez
Journal of Surgical Research, 1990
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Kinetics of the inhibition of xanthine dehydrogenase and of the reversible and irreversible forms of xanthine oxidase by silibinin and bendazac
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Environmental Toxicology and Pharmacology, 1996
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Xanthine oxidase-derived superoxide causes reoxygenation injury of ischemic cerebral endothelial cells
Joel Beetsch
Brain Research, 1998
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Binding of xanthine oxidase to glycosaminoglycans limits inhibition by oxypurinol
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Journal of Biological …, 2004
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Effects of the xanthine oxidase system on cardiac function in anaesthetised rats
Sarra Laycock
Free Radical Biology and Medicine, 1993
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Characterization of xanthine oxidase inhibition by anacardic acids
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Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2004
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Xanthine Oxidase Inhibition Attenuates Endothelial Dysfunction Caused by Chronic Intermittent Hypoxia in Rats
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Respiration, 2011
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Pharmacodynamics of oxypurinol after administration of allopurinol to healthy subjects
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British Journal of Clinical Pharmacology, 2003
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Binding of Xanthine Oxidase to Vascular Endothelium. KINETIC CHARACTERIZATION AND OXIDATIVE IMPAIRMENT OF NITRIC OXIDE-DEPENDENT SIGNALING
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Journal of Biological Chemistry, 1999
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Xanthine Oxidase: Isolation, Assays of Activity, and Inhibition
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Xanthine Oxidase Inhibitor, Allopurinol, Prevented Oxidative Stress, Fibrosis, and Myocardial Damage in Isoproterenol Induced Aged Rats
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Effects of Allopurinol on Ischemia and Reperfusion in Rabbit Livers
Ivarne Tersariol
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In vivo reactive oxygen species production induced by ischemia in muscle arterioles of mice: involvement of xanthine oxidase and mitochondria
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Xanthine Oxidase Is Involved in Free Radical Production in Type 1 Diabetes: Protection by Allopurinol
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Diabetes, 2002
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Nitro-oleic Acid, a Novel and Irreversible Inhibitor of Xanthine Oxidoreductase
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Human umbilical vein endothelial cells submitted to hypoxia-reoxygenation in vitro: Implication of free radicals, xanthine oxidase, and energy deficiency
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Journal of Cellular Physiology, 1992
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Xanthine oxidase inhibitors in ischaemic heart disease
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Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure results from 2 placebo-controlled studies
David Reaveley
2002
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Hydrogen peroxide is the major oxidant product of xanthine oxidase
Umair Malik
Free Radical Biology and Medicine, 2010
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