Journey towards periodontal regeneration (original) (raw)
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Pathway towards Periodontal Regeneration: A Review
2016
Periodontal regeneration has become one of the primary objectives of periodontal therapy. The resulting scientific endeavours have elucidated modes of periodontal wound healing, the growth of periodontal cells and their association with the surrounding matrix, and growth-promoting factors. The periodontal regeneration industry is producing better and more expensive devices, but the criteria for evaluating their success have not progressed to the same extent. Although clinical measurements of attachment level and probing depths, along with radiography, are good methods of evaluating tooth survival and prognosis, they do not indicate true biological regeneration. The goals of periodontal therapy include not only the arrest of periodontal disease progression, but also the regeneration of structures lost to disease, where appropriate. Conventional surgical approaches (e.g., flap debridement) continue to offer time-tested and reliable methods to access root surfaces, reduce periodontal p...
Periodontal regeneration in clinical practice
Medicina oral, patología oral y cirugía bucal, 2006
The regeneration or restitution of lost supporting tissue has always been considered the ideal objective of periodontal therapy. However, attempts to convert this intention into solid clinical practice can become tremendously complex, the results of which are very different from the original intention. The aim of this article is to offer an up-to-date, general perspective on periodontal regeneration, orienting the clinician within the global strategy for oral treatment. To this end, we revise the healing process of periodontal injury, the different therapeutic approaches, the interpretation of the results, and finally, limiting factors in periodontal regeneration.
New regenerative strategies in periodontics
Clinical dentistry reviewed, 2017
The progressive inflammatory process, which leads to the destruction of the gingival connective tissue and subsequently of the alveolar bone, periodontal ligament (PDL), and cementum on the root surface, if left untreated will eventually lead to the loss of the involved tooth or implant. Regeneration of lost periodontal tissues has always been the primary goal of treatment; however, this has proven to be an extremely challenging task. Keywords Periodontal treatment Á Regenerative procedures Á Bone grafts Á PDL Quick reference/description The progressive inflammatory process, which leads to the destruction of the gingival connective tissue and subsequently of the alveolar bone, periodontal ligament (PDL), and cementum on the root surface, if left untreated will eventually lead to the loss of the involved tooth or implant. Regeneration of lost periodontal tissues has always been the primary goal of treatment; however, this has proven to be an extremely challenging task.
Journal of periodontology, 2005
Untreated periodontal disease leads to tooth loss through destruction of the attachment apparatus and tooth-supporting structures. The goals of periodontal therapy include not only the arrest of periodontal disease progression,but also the regeneration of structures lost to disease where appropriate. Conventional surgical approaches (e.g., flap debridement) continue to offer time-tested and reliable methods to access root surfaces,reduce periodontal pockets, and attain improved periodontal form/architecture. However, these techniques offer only limited potential towards recovering tissues destroyed during earlier disease phases. Recently, surgical procedures aimed at greater and more predictable regeneration of periodontal tissues and functional attachment close to their original level have been developed, analyzed, and employed in clinical practice. This paper provides a review of the current understanding of the mechanisms, cells, and factors required for regeneration of the perio...
Regeneration in Periodontal Surgery: A Review
The diseases of the periodontium are common, aff ecting up to 90% of the global inhabitants. The mildest form of periodontal disease presents itself as gingivitis, which is reversible and mainly caused by the bacterial biofi lm on teeth and adjacent gingiva. Whereas, periodontitis is the moderate to severe form of periodontal disease and results in loss of connective tissue and bone support and is one of the major causes of adult tooth loss. The ultimate goal of periodontal treatment is to prevent further attachment loss and regenerate periodontal supporting tissues. To achieve successful periodontal regeneration, various therapeutic strategies are available. Over the past two decades, a variety of pharmacological agents have also been studied for regeneration of lost periodontal structures. This informational review paper describes the various pharmacological agents which are considered important for promoting periodontal regeneration.
Regeneration of the Periodontal Apparatus in Aggressive Periodontitis Patients
The aim of this article is to evaluate and compare, retrospectively, the efficacy of two regenerative periodontal procedures in patients suffering from aggressive periodontitis (AgP). Twenty-eight patients were diagnosed with AgP, suffering from multiple intra-bony defects (IBD); that were treated by one of two regenerative modalities of periodontal therapy randomly assigned to each patient: a. guided tissue regeneration (GTR) or b. an application of enamel matrix derivatives (EMD) combined with DBX. The monitoring of the treated sites included recordings of probing depth (PD), clinical attachment level (CAL), and gingival recession. Pre-treatment and follow-up (up to 10 years from the surgery) recordings were analyzed statistically within and between groups. A significant reduction was shown at time on PD and CAL values, however, not between subject groups. CAL values decreased in all sites. At EMD group (44 sites) CAL gain was 1.92 mm (±1.68) from pre-treatment to follow-up...