18-P-06 - Evaluation of mesoporous silicas as stationary phases for high performance liquid chromatography (HPLC (original) (raw)

Four mesoporous silicas, formed of isometric particles with 2.8 nm and 5.6 nm pores, were prepared by varying the synthesis conditions (silica source, surfactant, pH and temperature). A part of each sample was silylated with C8 chains. The silanol and silyl groups contents were estimated by 29Si NMR. Good separations have been obtained on mixtures of aromatic molecules by normal-phase HPLC with the four materials. In reversed-phase HPLC the results exhibit differences in function of the pore filling by the silyl groups.