Radiation-Induced Nausea and Vomiting (RINV) (original) (raw)

2017

Abstract

Radiation-induced nausea and vomiting (RINV) is generally less frequent and less severe than the nausea and vomiting encountered in patients receiving chemotherapy. This problem is often underestimated and undertreated by radiation oncologists in clinical practice; however, it can be very distressing and may cause delay or even interruption of radiotherapy [1–3]. The incidence of RINV was studied in two prospective observational studies. The Italian Group for Antiemetic Research in Radiotherapy (IGARR) analyzed the incidence of RINV in 1020 patients receiving various kinds of radiation therapy without concurrent chemotherapy. Vomiting and nausea occurred in 11% and 27.1% of patients, respectively, and 27.9% of patients had both vomiting and nausea [1]. Nausea was twice as frequent as vomiting (27.1% vs. 11%) and lasted longer (median duration 10 vs. 3 days). The RINV incidence rates based on anatomical sites were 28% for breast, 39% for pelvis, 40.4% for head and neck, 48.8% for tho...

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