Therapeutic approach for COVID-19: The power of herbal medicine (original) (raw)
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International Journal of Biomaterials
The COVID-19 pandemic has once again prompted people to resort to the remedies of folk and alternative medicine. Medicinal plants, because of their chemical composition, pharmacological properties, and the action of biologically active substances, can stop and relieve the symptoms of the disease. The purpose of the work is a comparative flora analysis of medicinal plants to identify the most prospective plant and further production of a remedy for the avoidance, treatment, and rehabilitation of COVID-19. The search for prospective medicinal plants was performed by analyzing the literature in online databases: Web of Science, Scopus, Google Scholar, and PubMed, including official WHO media sites. According to recent studies related to COVID-19, a significant number of medicinal plants with anti-inflammatory, antiviral, and immunostimulatory effects have been identified. A comparative study of nine medicinal plants was conducted to determine the most suitable medicinal plant to treat ...
The Potentials of Medicinal Plants in the Treatment of Covid-19 Patients: A Review
International Journal of Pharmacognosy & Chinese Medicine
COVID-19 pandemic (corona virus disease 2019 is a life threatening SARS-Cov-19 severe acute respiratory syndrome virus 2) situation that was declared a public health emergency by WHO in early 2020. Today’s primary emphasis is on the treatment of COVID-19 yet the specific mode of action of antiviral agents being employed must be identified. At present, the human on risk are being vaccinated but there is no clear anti-COVID 19 medicine. This study focuses on herbal approaches as a potential alternative therapy for COVID-19, based on medicinal plants. Some herbs are well-known in different traditional medicines for prevention, cure and recovery of the diseases like COVID-19. Mostly the plant’s herbal extract inhibits viral replication; however several studies have shown that conventional herbal extracts may interact with important viral proteins associated with the virulence. The update on traditional medicines suggested for the prevention of COVID-19 has been analyzed here.
Herbal therapy in Covid-19: A systematic review of medicinal plants effective against Covid-19
Caspian Journal of Environmental Sciences, 2023
In 2019, a new disease called Covid-19 was detected in Wuhan located in China which caused seriously disease or death at any age. This disease has various symptoms such as fever, chills, cough, sore throat, headache, body pain, muscle pain, diarrhoea, and vomiting. In this review study, articles related to the subject were searched using scientific sites such as Medline, PubMed, and Google Scholar using the keywords of traditional medicine, medicinal plants, and Covid-19. After downloading the articles, irrelevant articles were removed and related articles were reviewed. According to the results obtained from the review of the literature, the effective medicinal herbs including Zingiber officinale, Alpinia officinarum, Cinnamomum zeylanicum, Nigllea sativa, Citrus paradise, Laurus nobilis L. and Echinacea purpura were the most important medicinal herbs used in treatment of Coronavirus. Antiviral chemical drugs usually inhibit the virus by disrupting the key protein and viral virulence factors. Probably, medicinal plants inhibit corona virus with a mechanism similar to the chemical drugs. Therefore, it is possible to produce effective herbal medicines as alternative for synthetic drugs and reduce the pain and suffering from Covid-19 in patients.
Efficacy of Herbal Medicines as Remedies against COVID-19
EAS Journal of Pharmacy and Pharmacology
Objective: Coronaviruses belong to the order Nidovirales, family Coronaviridae, and four genera, namely: alpha, beta, gamma, and delta. In December 2019, a novel coronavirus was first officially reported in Wuhan City of China. Consequently, on February 11, 2020, the CSG named the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); it causes the disease dubbed Covid-19. The virus was officially declared pandemic by WHO, on March 11, 2020. Up till date, no drug, including the existing ones, has been approved for covid-19 treatment. The objective of this work, is to carry out a review on proven herbal extracts and the phyto-compound contents, for possible antiviral properties against SARS-CoV-2, and thus, as potential candidates for Covid-19 vaccine. Materials and Methods: Investigation into proven plant species against respiratory tract diseases was carried out between 1st to 30th of July, 2020 via: (a) Conduction of interview with traditional herbal healers and users...
Herbal medicine, a reliable support in COVID therapy
Journal of Immunoassay and Immunochemistry
At present, specific therapies for COVID-19 are not well established, being certain only that the immune system plays a decisive role in the initiation and progression of the disease. Plants have given and continue to give compounds with great efficiency and low toxicity, some of them being a starting point for extremely effective synthetic substances. Although herbal remedies are used mainly for preventive purposes, there are also guidelines issued by some countries that indicate the use of traditional remedies for different stages of COVID-19 disease.Europe has a long and strong tradition of using medicinal plants for therapeutic purposes, but clinical trials for this type of approach are scarce, compared to Asia. In this regard, a bridge between tradition and science, would have a strong impact on the capacity for prevention and treatment of COVID-19. The paper reviews compounds of plant origin that have previously proven effective in counteracting some coronaviruses but also some of their major effects-direct action on virus replicative apparatus (viral entry or replication, action on the viral enzymatic system), collateral action of natural compounds on the immune system and also the contribution of herbal medicine as vaccine adjuvants are tackled.
Investigation of the usage of herbal products during the Covid-19 pandemic
Journal of Research in Pharmacy, 2021
During the COVID-19 pandemic period, herbal products have been used by patients for many purposes. In this study, the frequency of use of herbal products during the COVID-19 pandemic was investigated. This research is a cross-sectional study. Patients who admitted to an academic hospital (Gazi University Faculty of Medicine) Chest Diseases Clinic between November 2020-January 2021 were included in the study. It was concluded that approximately 32% of the patients used herbal products during the pandemic period and that the purpose of most of the participants was to strengthen the immune system. It was observed that the participants first consulted the spice sellers about the medicinal plants used against COVID-19. As a result, it has been determined that patients from many segments of society use herbal products against COVID-19 and they generally learn about the use of these products from nonmedical sources. In this work, as it is always emphasized in terms of human health, the imp...
COVID-19 Crisis, Herbal Medicines, and Natural Products - Concerns and Suggestions
Jundishapur Journal of Natural Pharmaceutical Products
Since the outbreak of the COVID-19 pandemic in the last days of 2019 in China, medical experts and organizations worldwide have proposed guidelines for its prevention and treatment. However, despite the availability of state-of-the-art technologies, modern medicine specialists have so far not been successful in controlling it. This has led traditional medicine experts to propagate their knowledge to prevent and cure COVID-19, creating an open debate. According to scientific literature, traditional medicine experts claim beneficial effects of herbal medicines against viral infections and their effectiveness in controlling the symptoms of respiratory disorders. Modern medicine specialists express their concerns about the quality, safety, and efficacy of herbal medicines, in addition to the risk of herb-drug interactions and the lack of randomized clinical studies. Herbal medicines have been popular since prehistoric times, and during the COVID-19 pandemic, they are increasingly used worldwide. The lack of definite cure and the high cost of available modern medicines have also promoted the use of herbal medicines. An evidence-based approach using herbal medicines with proven antiviral activities or containing compounds providing symptomatic relief in COVID-19 can be considered for clinical studies. The interaction of herbal medicines with modern drugs should also be considered in patients taking them. Traditional and modern medicine aim to provide effective and safe treatment and prevent COVID-19 infection. Considering the ground realities of the COVID-19 crisis and keeping in view the worldwide use of herbal medicines, in our opinion, the pros and cons of their use should be carefully weighed, and practical solutions should be considered.
Herbal Medicine as an Alternative Method to Treat and Prevent COVID-19
Baghdad Journal of Biochemistry and Applied Biological Sciences
Background: The current outbreak of the serious respiratory syndrome disease COVID-19 has resulted from a novel coronavirus (SARS-CoV-2). This infectious disease was classified as a pandemic by the World Health Organization (WHO) because it is threatening public health and life worldwide. Recently, restrictions in many countries are applied to detect the infected individuals and isolate them, in addition to attempts to find appropriate treatments that can help decrease the severe symptoms of the disease. Regardless of the conduced efforts, the number of reported cases of coronavirus infections is still growing up. Yet, no medication or vaccine was approved to prevent and/or treat people from this coronavirus, though many researches from academic groups and medication companies are still ongoing. Objective: This review aims to summarize the possible herbs and plants from the natural herbal medicine along with western medicine, which could assist treat or protect people from COVID-19...
ROLE OF NATURAL PRODUCT IN PREVENTING COVID-19
The current pandemic of COVID-19 that is spreading across countries originated in Wuhan, China. The single cause of this highly communicable disease is a novel coronavirus, called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the seventh known virus of the Coronaviridae family capable of infecting humans. The World Health Organization (WHO) welcomes innovations around the world including repurposing drugs, traditional medicines and developing new therapies in the search for potential treatments for COVID-19. In this study the effectiveness of certain medicinal plants for mild and moderate Covid-19 patients were analyzed literately. Thirty number of plants were studied according to their phytochemical properties, traditional uses, therapeutic actions and certain in-vitro studies from articles published in international multidisciplinary journals, newspapers, books, recognized health organizations websites and interviews from the clinicians. The results showed that the plants possess certain phytochemicals which would be effective to boost the immune system, preventing the viral load in the human host, reduce the inflammatory cytokines and improve the blood cells. However pre-clinical and clinical studies should be conducted to prove the efficacy in scientific manner.