Localized Hepatic Tuberculosis Presenting as Fever of Unknown Origin (original) (raw)
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Hepatic Tuberculosis: Uncommon Presentation of A Common Disease-A Case Report with Literature Review
Hepatic tuberculosis is a rare form of tuberculosis with non specific signs and symptoms which requires a high index of suspicion to reach a diagnosis. Usually has three forms of presentation in the form of miliary tuberculosis with liver involvement, granulomatous hepatitis and local hepatic tuberculosis. Usually requires guided tissue sample with histopathological examination for diagnosis. Here we are reporting a case of hepatic tuberculosis with multiple hepatic nodules who presented with fever and non specific symptoms and treated with anti-tubercular drugs followed by resolve of signs and symptoms.
Case Report of Isolated Hepatic Tuberculosis
Bangladesh Journal of Medicine, 2015
Tuberculosis is one of the most common diseases in Bangladesh and has variable clinical manifestations. Isolated Hepatic tuberculosis is not a common disease; in fact the presentation of hepatic tuberculosis may be without having history of any active Pulmonary TB or military TB. Patient usually present without having any typical symptoms; so it is difficult for a physician to diagnose the disease quickly. Patient presenting with space occupying lesion in liver is confused with abscess, hepatoma or metastases. Here we are presenting a case report of isolated hepatic tuberculosis.
Atypical Liver Lesions: Primary Hepatic Tuberculosis
2018
Hepatic tuberculosis is seen in 50-80% of patients with disseminated tuberculosis. However, isolated hepatic tuberculosis is rarely encountered in an immunocompetent patient, even in regions with high prevalence of tuberculosis. We report a case of a 43-year-old male who underwent triphasic computed tomography (CT) scan for an uncharacterized hypoechoic liver lesion found on ultrasound. CT scan revealed multiple ill-defined areas in segments VI and IV of the liver, which were reported as atypical liver lesions. Differentials of atypical hepatoma versus hepatic metastasis from an unknown primary were given. Subsequently, biopsy of the lesion was performed and histopathology report revealed chronic granulomatous inflammation with tuberculosis as a likely possibility. The patient was started on antituberculous therapy and responded to treatment. This case emphasizes the diagnostic difficulties of hepatic tuberculosis and the significance of considering this differential in patients wit...
Primary/local hepatic tuberculosis without dissemination
Case Reports, 2015
We present a rare case of primary hepatic tuberculosis in a 50-year-old man who presented with pain at the right hypochondrium. The diagnosis was established by fineneedle aspiration cytology (FNAC) of the primary hepatic lesions in both lobes of the liver, which was further supported by histopathological examination and tissue PCR for Mycobacterium tuberculosis in the FNAC specimens.
Primary hepatic tuberculosis presenting as acute liver failure
Oxford medical case reports, 2014
Abdominal tuberculosis is a common clinical entity in Indian subcontinent; however, hepatic tuberculosis in the absence of miliary abdominal tuberculosis is restricted to the case reports and small case series in English literature. It mimics common liver diseases like liver abscess and tumors. We report a case of 25-year-old immunocompetent female who presented with features of acute liver failure. Ultrasonography (USG) abdomen revealed multiple hypoechoic lesions. However, patient expired within 48 h of presentation but her liver autopsy revealed multiple epithelioid cell caseating granulomas with positive staining for acid fast bacilli (AFB). Polymerase chain reaction (PCR) was also positive for Mycobacterium tuberculosis.
Isolated hepatic tuberculosis: A rare cause of hepatic mass lesions
The Turkish Journal of Gastroenterology, 2014
Hepatic tuberculosis usually accompanies pulmonary and extrapulmonary tuberculosis. Although isolated hepatic tuberculosis is a very rare condition, it should be considered in the differential diagnosis of a hepatic mass. Here, we report a 42-year-old woman presenting with weight loss, fever, night sweats, and a hepatic mass on the abdominal ultrasonography and magnetic resonance imaging (MRI). Ultrasonography-guided percutaneous needle biopsy demonstrated a caseating granuloma with epithelioid histiocytes and giant cells compatible with the diagnosis of tuberculosis. The patient was treated with four anti-tuberculous drugs for 1 year. She recovered clinically, and her post-treatment abdominal MRI was normal.
Journal of Indian Association of Pediatric Surgeons, 2005
Hepatic tuberculosis is usually associated with an active pulmonary or miliary tuberculosis, but rarely localizes as a liver tumor mass. The clinical presentation of isolated liver tuberculosis is so rare and atypical that it challenges the clinical acumen of the treating physician. Diagnostic modalities like ultrasound and computed tomography can miss the diagnosis. Ultimately, the diagnosis is confirmed by demonstrating an acid fast Mycobacterium in aspirated pus or necrotic material.
Isolated Hepatic Tuberculosis-Serohepatic Type Dr
2017
Though tuberculous infection constitutes one of the more common causes of death and morbidity in the developing world, hepatic tuberculosis is a rare presentation. Hepatic involvement, usually in the form of multiple small-sized miliary nodules, is seen along with other organ involvement. In contrast, isolated hepatic tuberculosis is seldom encountered in clinical practice. In this article we highlight about the serohepatic tuberculosis which is a rare presentation among other hepatic tuberculosis types. Uniquely, the patient had sub capsular as well as extra-capsular involvement. Diagnosis involved imaging and histopathological examination. Keyword: USG, CT, Tuberculoma, Hepatic tuberculosis.
An autopsy study of pathology of liver in tuberculosis
innovative publication, 2017
Background: Hepatic tuberculosis (TB) is an uncommon manifestation of tuberculosis. The term hepatobiliary TB refers to either isolated hepatic or hepatobiliary involvement with other organ involvement Methods: A five year autopsy study conducted of 236 adult cases of tuberculosis. Clinical details of all cases were obtained from hospital records. Sections from the liver were processed routinely and histopathological findings along with Clinical & biochemical findings were analysed in detail. Results: Commonest age group affected was 31 to 40 years of age with a male: female ratio of 1.29:1. Fever was present in (56.6%). Hepatomegaly along with abdominal pain was significantly associated with Hepatic involvement by TB. Pulmonary and extra pulmonary tuberculosis was seen in 177 and 59 cases respectively. Liver involvement was mainly secondary except in one case. The spectrum of histopathological changes of the liver showed epitheliod cell granulomas in (41.5%), fatty changes in (46.6%), inflammation in (16.5%) and fibrosis in (3.8%) cases. On comparing the liver TB and non-liver TB cases, it was found that fatty changes were more common but there was no difference in the degree of fibrosis in the two groups. Comparing liver function tests, available in 213/236 cases, 61% were abnormal. Deranged AST (65%), ALT (62.05%) & ALP (57. 05%) was seen in hepatic TB cases. Conclusion: Liver involvement was mainly in the form of secondary tuberculosis. Fever, hepatomegaly, abdominal pain, fatty change and caseating granulomas along with deranged liver enzymes are significantly associated with hepatic involvement in cases of tuberculosis.