Prescribing patterns of antihypertensive drugs in tertiary care teaching hospital (original) (raw)
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Journal of Drug Delivery and Therapeutics
Aim/Background: To assess the prescribing pattern of anti-hypertensive and to assess the risk factors associated with hypertension. Materials and methods: The prospective observational study was carried out for 6 months among 31 in-patients in the various departments of Yenepoya Medical College Hospital, Mangalore. Patients of both sex aged 18 years and above, those who can understand oral and written information and those diagnosed with hypertension were added in the study. Out-patients, patients with mental or psychiatric diseases, cognitive dysfunction, patients on cancer chemotherapy, pregnant and lactating females were excluded. A suitably designed data collection form was prepared to collect the data. Results: Out of 31 patients, hypertension was mainly affected in males above the age of 60years. In the study, majority (41.9%) of the participants had Stage II Hypertension according to JNC 7 classification. The major risk factors associated with Hypertension was advanced age (...
International Journal of Basic & Clinical Pharmacology, 2017
Hypertension is a disease of complex etiology, affecting 972 million people worldwide. Prevalence of hypertension in India is reported to vary from 4 to 15% in urban and 2-8% in rural population. 1 It is a leading risk factor for coronary heart disease, stroke and chronic renal disease. Evidence from large clinical trials now suggests that lowering blood pressure effectively prevents these adverse outcomes. 2,3 Selection of antihypertensive agents should therefore be based primarily on their comparative ability to prevent these complications. Therefore, it is important that once the diagnosis of hypertension is established, blood pressure should be controlled adequately through regular follow-up, lifestyle modification, exercise and effective antihypertensive drugs. 4 Drug utilization studies which evaluate and analyze the drug therapy in hypertension and hypertension associated diseases is very essential from time to time to observe the prescribing attitude of physicians with the aim of rational use of drugs and to minimize the adverse drug reactions. 5,6
A Study on Prescribing Pattern of Antihypertensives at a Tertiary Care Hospital
ijpsr.com
The retrospective study on prescribing patterns of antihypertensives showed that the prevalence of hypertension was predominantly more with male patients than in female patients. It was also found that the average age of the overall study population was 56 years. The average age of the population clearly indicates the elderly patients were affected more. The results indicates that around 57.6% of the patients were brought to normal or prehypertension after the successful treatment with antihypertensive agents. The remaining 42.4% were brought to high normal after the treatment. The study revealed that the physician were treated 44.73% of the patients population with Ramipril alone as mono therapy, 21.05% were treated with Atenolol, 10.52 % were treated with Amlodipine, and other patients are treated with Amiodarone, Prazonin HCL, and Telmisarten etc. The most commonly prescribed combination was found to be Ramipril with Atenolol and it is followed by Ramipril with Amlodipine. The overall percentages of these combinations were found to be 37.25 % and 25.0% respectively.
A Study on Drug Utilization Pattern of Antihypertensive Drugs in Tertiary Care Hospital
INDIAN RESEARCH JOURNAL OF PHARMACY AND SCIENCE, 2020
Background: The JNC 8 guidelines published in 2014 are the most recent guidelines for the management of hypertension in different clinical settings. antihypertensive drugs in concordance with the guidelines. Aim: The aim of the study is the utilization of anti Method: A total of 150 patients were recruit the pattern of utilization of antihypertensive drugs data was sorted on the basis of demographic characteristic, drug category. Result: It was found that prevalence of (48%). Most of the patients were found to have diabetes as the co morbid condition. The prescribed category of antihypertensive drugs utilized were (68.6%), diuretics (45.4%), calcium channel blocker (38%), beta blocker (26.6%) and alpha blockers (3.4%). ACEI/ARB was the most frequently prescribed antihypertensive class of drug. Conclusion: ACEI/ARB was the most common a for better therapeutic outcomes.
International Journal of Medical Science and Public Health, 2014
Background: Irrational drug prescribing is a common practice globally; it results in increased morbidity, mortality & economic burden on society. Drug utilisation studies are an important tool to promote rational prescribing. Aims & Objective: To study on drug prescribing pattern in hypertensive patients. Materials and Methods: A drug utilisation study was conducted in hypertensive patients by the department of pharmacology in medicine OPD at SGRRIM & HS, Dehradun for 6 months. 645 prescriptions were evaluated for prescribing pattern by using WHO drug use indicators. Results: 645 prescriptions were analysed. A total of 1828 drugs were prescribed. 697 (38.13%) antihypertensives, 243 (13.30%) antidiabetics, 174 (9.52%) non-steroidal anti-inflammatory drugs (NSAIDs), 154 (8.44%) statins, 114 (6.24%) thyroid hormone, 54 (2.95%) anti-anxiety/antidepressants and 392(21.44%) miscellaneous drugs were prescribed. 697 antihypertensive drugs were prescribed. 234 (33.57%) angiotensin receptor blockers (ARBs), 117 (16.79%) angiotensin converting enzyme (ACE) inhibitors, 95 (13.63%) Beta blockers, 83 (11.91%) Calcium channel blockers 168 (24.10%) Fixed dose combinations (FDCs) of antihypertensives were included. 2.83 drugs were prescribed per prescription. 225 (32.28%) antihypertensives were prescribed from essential medicine list. Conclusion: Most commonly prescribed drugs were ARBs and ACE inhibitors. Rational prescribing requires consideration to dose and duration and interaction with other medications.
International Journal of Research in Medical Sciences, 2018
Background: Hypertension is one of the most common chronic diseases leading to high mortality and morbidity. In order to prevent complications and to improve the patient survival, the early and efficient management of essential hypertension is very much needed. In this context, the use of established anti-hypertensives assumes paramount importance. Objective was to study the prescribing pattern of anti-hypertensive drugs in a tertiary care teaching hospital in north India.Methods: It was a cross-sectional observational study involving 205 prescriptions for patients suffering from primary essential hypertension in the Medicine Outpatient Department of Acharaya Shri Chander College of Medical Sciences and Hospital, Sidhra, Jammu, J and K. All hypertensive patients irrespective of age and sex visiting OPD and treated with at least one hypertensive drugs were included in the study. Data was obtained from the patients by scrutinizing the out patients regarding the demographic profile and...
International Journal of Pharmacological Research, 2017
Introduction: Hypertension is the increased systolic blood pressure of ?140 mm Hg or diastolic blood pressure of ?90 mm Hg. The antihypertensive drugs currently available are chosen on the basis of their efficacy, side-effects, and cost. Accordingly, a need to survey the pattern of usage of antihypertensive drugs is must, to see if the current usage is rational and in concordance with current guidelines for treatment of hypertension. Therefore this study was carried out with the aim of analyzing the pattern of antihypertensive drugs being prescribed and its adherence with JNC-8 guidelines, in a tertiary care Teaching hospital of Andaman & Nicobar Islands, India.Material & methods: A cross-sectional, observational study was done in ANIIMS, Port Blair, India over a period of 6 months from October 2016 to March 2017, in which analysis of the prescriptions of patients of essential Hypertension was done. A total of 870 prescriptions were analyzed based on age group, gender, number of ant...
ANTI HYPERTENSIVE MEDICATION PRESCRIBING PATTERNS IN A UNIVERSITY TEACHING HOSPITAL IN SOUTH DELHI
To investigate the use of antihypertensive drugs in hypertensive patients and to identify whether such pattern of prescription is appropriate in accordance with international guidelines for management of hypertension. Methods: This was a prospective analysis. A prescription based survey among patients with established hypertension was conducted at the Medicine Out-Patient Department of University Teaching Hospital in South Delhi, India. Data were collected from patients' medical records as well as patients' interviews. Results: A total of 192 hypertensive patients fulfilled the criteria for inclusion in the study analysis. Combination therapy was used more commonly than monotherapy (54.6% vs 45.4). Among the monotherapy category, the various classes of drugs used were as follows: beta-blockers (28.8%), diuretics (24.1%), calcium channel blockers (21.8%), ACE inhibitors (18.4%), angiotensin II receptor blockers (5.7%) and α 1-blocker (1.1%). With respect to overall utilization pattern, diuretics (42.2%) were the most frequently prescribed class, beta-blockers (41.2%) ranked second followed by calcium channel blockers (39.1%), ACE inhibitors (26.0%), angiotensin II receptor blockers (23.4%) and α 1-blocker (9.4%). As for individual medicines, amlodipine (35.4%) was the most commonly prescribed antihypertensive drug followed by atenolol (17.8%), ramipril (17.2 %) and furosemide (13.0 %). Among the combination therapies, 2-drug treatment was preferred for 75% of the hypertensive patients with CCB and β-blocker being the most frequent drug combination (22.4%). Conclusion: The general pattern of antihypertensive utilization seems to be in accordance with the international guidelines for management of hypertension.
Study on Prescribing Pattern of Antihypertensive Drugs in a Tertiary Care Hospital
Advances in Pharmacology and Pharmacy, 2017
Objective: To analyze prescription pattern of antihypertensive drugs in patients with hypertension alone and with coexisting diseases. Methodology: A descriptive cross-sectional study was conducted in outpatient department of tertiary care hospital in south India. A total of 286 prescriptions of patients diagnosed to have hypertension with or without coexisting diseases were collected. Details of prescriptions were entered in the preformed pro forma and analyzed. Result: The study included 138 (48.25%) male and 148 (51.75%) female. Out of 286 hypertensives, 122 (42.66%) patients were having co-existing type 2 diabetes mellitus (T2DM). And remaining 164 patients (57.34%) were only hypertensives. Out of 286 patients, 227 (79.31%) patients were on monotherapy, 49 (17.13%) were on dual therapy and remaining 10 patients were on triple anti-hypertensive drugs. Among 150 antihypertensive drugs that are prescribed for hypertensive patients withT2DM, 57 (38%) were calcium channel blocker (CCB), 40 (26.66%) were angiotensin converting enzyme inhibitors (ACEI), 31 (20.66%) were angiotensin receptor blockers (ARB), 13 (8.66%) were diuretics and remaining 9 (6%) were beta blockers. Similarly, among 206 antihypertensive drugs prescribed for hypertension alone patients, 97 (47%) were CCB, 37 (17.96%) were ACEI, 31 (15%) were ARB, 26 (12.62%) were diuretics and remaining 15 (7.28%) were beta blockers. Conclusion: The study has shown that majority of patients were on monotherapy (79.31%) and calcium channel blockers were commonly prescribed for hypertension in patients with or without type 2 diabetes mellitus followed by ACE inhibitors, ARB and beta blockers.
Prescribing Trend of Antihypertensive Drugs in Sri Ganganagar District: A Retrospective Study
Objective: The choice of drug for the treatment of hypertension changes at short intervals. Drug utilization studies conducted at regular intervals help to guide the physician in prescribing drugs rationally. The present study was done to analyze the prescribing patterns of antihypertensive drugs in a North Indian hospital. Material & method: A retrospective, cross sectional analysis of prescriptions of antihypertensive cases admitted in Medicine in-patient wards of civil hospital of Sri Ganganagar was conducted. All the prescription files with diagnosis of essential hypertension were analyzed. Prescriptions for hypertension with other co-morbid conditions were also included. Frequency and proportions of utilization of antihypertensive medications were charted and figured. Result: During the study period, there were 435 prescriptions for essential hypertension. The most frequently prescribed antihypertensive medications were: monotherapy (42.06%), (57.94%) of patients were on multiple drug therapy, the most favored fixed drug combination being diuretics with angiotensin receptor blockers (31.74%). Conclusion: The present study revealed that Angiotensin receptor blockers are the drugs of choice as monotherapy and as combination therapy for hypertensives. This pattern of prescription is also supported by the current JNC VIII guidelines for the treatment of hypertension.