Effect of Extract and Caffeic Acid Phenethyl Ester on Apoptosis of Odontoblast Cells (original) (raw)

Indian Journal of Forensic Medicine & Toxicology, 2021

Abstract

Background: Propolis is a resinous hive product collected by bees from tree buds and mixed with secretedbee wax to both avoid bacterial contamination in the hive and seal it. It is known to have a wide spectrumof pharmacological properties, including anti-inflammatory, antioxidant, antibacterial, antiviral, and antifungal abilities. Apoptosis tests were performed on odontoblast cells in rats (Rattus novegicus) to assessthe viability of propolis extract and caffeic acid phenetyl esters (CAPE) as alternative candidates for pulpcapping agents in conservative dentistry treatment. Objective: To examine the apoptosis activity of propolisextract and CAPE as capping materials on odontoblast cells. Methods: This study was designed as a posttest only control group laboratory experiment. The rats were randomly divided into three groups. Pulpexposures were performed on the occlusal surface of the right maxillary first molars. In the first group, thecontrol group, glass ionomer cement (GIC) was ...

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