The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1 (original) (raw)
Crystal structure of HIV1 reverse transcriptase in complex with a polypurine tract RNA:DNA
kalyan das
Embo Journal, 2001
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Human Immunodeficiency Viral Reverse Transcriptases: Analyses of the Active Sites of the Polymerase Domain and Drug-Resistant Mutants of the Reverse Transcriptases
Peramachi Palanivelu
World Journal Of Advanced Research and Reviews, 2024
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Quantitative Structural Rearrangement of HIV-1 Reverse Transcriptase on Binding to Non-Nucleoside Inhibitors
Luckhana Lawtrakul
Monatshefte f�r Chemie/Chemical Monthly, 2004
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Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer
Lori Kohlstaedt
Proceedings of the National Academy of Sciences, 1994
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2.2 å resolution structure of the amino-terminal half of HIV-1 reverse transcriptase (fingers and palm subdomains)
Stefan Knight
Structure, 1994
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Structural aspects of drug resistance and inhibition of HIV-1 reverse transcriptase
Stefan Sarafianos
Viruses, 2010
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A novel neutralization epitope on the 'thumb' subdomain of human immunodeficiency virus type 1 reverse transcriptase revealed by a monoclonal antibody
Akira Yamaguchi
Journal of General Virology, 1996
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Domain structure of the human immunodeficiency virus reverse transcriptase
Octavian Schatz
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Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1
Lori Kohlstaedt
Proceedings of the National Academy of Sciences of the United States of America, 1994
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Structure and Function of HIV1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition
kalyan kumar
Journal of Molecular Biology, 2009
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Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor α-APA R 95845 at 2.8 å resolution
Kalyan Das
Structure, 1995
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Dimerization of Human Immunodeficiency Virus Type 1 Reverse Transcriptase as an Antiviral Target
Eugene Skripkin
Current Pharmaceutical Design, 2006
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Human immunodeficiency virus reverse transcriptase substrate-induced conformational changes and the …
Brian Keith
Proceedings of the National Academy of Sciences
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An Expanded Model of Replicating Human Immunodeficiency Virus Reverse Transcriptase
Birgitta Woehrl
Biochemistry, 1995
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Crystal Structure of HIV‐1 Reverse Transcriptase Bound to a Non‐Nucleoside Inhibitor with a Novel Mechanism of Action
Marco Radi
Angewandte …, 2010
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A mutation at position 190 of human immunodeficiency virus type 1 reverse transcriptase interacts with mutations at positions 74 and 75 via the template primer
Paul L . Boyer
Antimicrobial agents and chemotherapy, 1998
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Catalytic properties of the reverse transcriptases of human immunodeficiency viruses type 1 and type 2
Amnon Hizi
Journal of Biological Chemistry, 1991
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The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design
David Stuart
Structure, 1995
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The N137 and P140 amino acids in the p51 and the P95 amino acid in the p66 subunit of human immunodeficiency virus type 1 (HIV1) reverse transcriptase are instrumental to maintain catalytic activity and to design new classes of anti-HIV1 drugs
Federico Gago
Febs Letters, 2005
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Crystal Structures of Zidovudine- or Lamivudine-Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptases Containing Mutations at Codons 41, 184, and 215
David Stuart
Journal of Virology, 2002
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Structure of HIV-1 Reverse Transcriptase with the Inhibitor β-Thujaplicinol Bound at the RNase H Active Site
Kalyan Das
Structure, 2009
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Mutational analysis of the ribonuclease H activity of human immunodeficiency virus 1 reverse transcriptase
Amnon Hizi
Virology, 1990
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Conformational Landscape of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Non-Nucleoside Inhibitor Binding Pocket: Lessons for Inhibitor Design from a Cluster Analysis of Many Crystal Structures
Kalyan Das
Journal of Medicinal Chemistry, 2009
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Characterization of the Reverse Transcriptase of a Human Immunodeficiency Virus Type 1 Group O Isolate
Miguel Quiñones-mateu
Virology, 1997
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The interplay of structure and dynamics: Insights from a survey of HIV-1 reverse transcriptase crystal structures
James Seckler
Proteins: Structure, Function, and Bioinformatics, 2013
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The Y271 and I274 Amino Acids in Reverse Transcriptase of Human Immunodeficiency Virus-1 Are Critical to Protein Stability
Olivier Schwartz
PLoS ONE, 2009
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Characterization of the p68/p58 Heterodimer of Human Immunodeficiency Virus Type 2 Reverse Transcriptase
satish sharma
Biochemistry, 1996
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