The investigation of IL-1β and oxytocin levels among teenager with primary dysmenorrhea (original) (raw)
IOP Conference Series: Earth and Environmental Science, 2021
Abstract
Primary dysmenorrhea is one of gynecological problems and it commonly occurred among adolescents and reproductive age women during menstruation with some complaints such as pain, cramps and back pain. In primary dysmenorrhea there is an increase of PGF2α levels, vasopressin (VAP), Oxytocin (OT), IL-6 and IL-1β level. The aim of this study was assessed the differences of IL-1β levels and oxytocin among adolescents with primary dysmenorrhea and without primary dysmenorrhea. The research design in this study used Case Control. The population of this study were all students of Health Science Faculty, Unipdu Jombang. The sample of this study was 16 respondents, and they were divided into 2 groups: the case group (n = 8) and the control group (n = 8) that met the inclusion and exclusion criteria. Sampling method used Purposive Sampling technique. The measurement of IL-1β and Oxytocin levels used ELISA method. The data were analyzed by using Independent Sample T-Test with α ≤ 0.05. The res...
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