Histopathological Pattern of Gynecological Malignancies at Tribhuvan University Teaching Hospital, Nepal: A 3 years Study (original) (raw)
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Clinical and Demographic Profile of Gynaecological Malignancies in Eastern India
Acta Scientific Cancer Biology, 2023
Introduction: Globally Carcinoma Breast is the most commonly diagnosed cancer and it is the leading cause of death among the females and carcinoma cervix comes on the 4 th position regarding the incidence and mortality (1) In India Carcinoma Cervix and Carcinoma Breast are the commonest cancer in females and it contributed 39.4% of total cancer in 2020. Worldwide female reproductive cancers are the main cause of cancer deaths in females, Common cancers are carcinoma breast, Carcinoma cervix and Carcinoma Endometrium, Carcinoma Ovary (4). Material and Method: All histologically proven cases of gynaecological malignancies including Breast registered under hospitalbased cancer registry were included in this. The total patient present in our hospital were distributed based on various demographic categories based on gender, age group and district of their residence. Result: Total 32057 cases have been registered from year 2014 to 2021. In which 15825 cases were females. 6718 cases were of gynaecological cancers. In which 3392 cases were of Carcinoma Breast, 2039 (30.8%) cases were of Carcinoma Cervix, 1103(16.42%) cases were of Carcinoma Ovary, 68 (1.01%) cases were of Carcinoma Endometrium, 77 cases (1.5%) cases of carcinoma corpus uteri, 39 (0.5%) cases were of carcinoma vulva. Conclusion: Retrospective analysis of 6718 cases was done with HBCR in the department of Radiation Oncology. • A total of 6718 cases were analysed. • Breast carcinoma was the most common malignancy which contributed about 10.58% of all the cancers and 50.49% of all the gynaecological malignancies. • Year wise distribution shown carcinoma cervix was commonest malignancy in the earlier years 2014-2018, After 2019 carcinoma cervix became the 2 nd commonest and carcinoma breast became the commonest malignancy among the gynaecological malignancies. • Common age of presentation 35-64 years in all the gynaecological cancers. • Lower Incidence shown in carcinoma breast and carcinoma ovary in elderly age group 65-85 years of age group. • Earlier age group was 13.9% in Carcinoma Breast and Carcinoma Ovary 20.9%, Carcinoma Vulva 15.3%, and carcinoma corpus uteri 14.2%.
An Overview of Ovarian Tumours at B.P. Koirala Memorial Cancer Hospital, Nepal
Nepalese Journal of Cancer, 2019
Introduction: Ovarian cancer is the seventh most commonly diagnosed cancer among women in the world. This study was conducted with the aim to find out different histological types of ovarian tumours reported at B.P. Koirala Memorial Cancer Hospital (BPKMCH), Chitwan, Nepal. Methods: This was a retrospective study carried out at the Department of Pathology of BPKMCH from January 1, 2018 to December 31, 2018. This study included the patients who were operated at BPKMCH or referred cases from elsewhere, but the specimen was processed and reported at BPKMCH. All the data were retrieved and analyzed from the records of Pathology Department. Results: Altogether 87 cases of ovarian tumours were reported during the study period. Out of which, 31 cases were benign ovarian tumours whereas 56 cases were malignant ovarian tumours. Both benign and malignant ovarian tumours were most common in age group 41 to 50 years of age. Among benign ovarian tumours, 12 cases were serous cystadenoma, 7 cases...
Gynecological cancers: A summary of published Indian data
South Asian Journal of Cancer, 2016
Gynecological cancers are among the most common cancers in women and hence an important public health issue. Due to the lack of cancer awareness, variable pathology, and dearth of proper screening facilities in developing countries such as India, most women report at advanced stages, adversely affecting the prognosis and clinical outcomes. Ovarian cancer has emerged as one of the most common malignancies affecting women in India and has shown an increase in the incidence rates over the years. Although cervical cancer is on a declining trend, it remains the second most common cancer in women after breast cancer. Many researchers in India have published important data in the field of gynecologic oncology, covering all domains such as basic sciences, preventive oncology, pathology, radiological imaging, and clinical outcomes. This work has given us an insight into the in-depth understanding of these cancers as well as the demographics and survival rates in the Indian population. This a...
International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2018
Background: The burden of malignancy and deaths due to it are rising worldwide. In women gynaecological malignancies are among the most common cancers. This study was undertaken to study the pattern and relative frequencies of gynaecological malignancies among women admitted in the Department of Gynaecology, at Saveetha Medical College and Hospital, Tamil Nadu.Methods: This is a retrospective observational study done at the department of Saveetha Medical College and Hospital over a period of two years from September 2015 to September 2017. Case records of women admitted in the Department of Gynaecology and diagnosed to have gynaecological malignancy were retrieved from the department of medical records. Information regarding demographic details, site of malignancy, histopathology of malignancy was analysed and expressed as percentages.Results: During the study period 49 cases of gynaecological malignancies were reported. Out of 49 cases, 36 cases were cancer cervix, followed by 7 ca...
Comprehensive study of ovarian tumours in Kathmandu University Hospital
Journal of Kathmandu Medical College, 2018
Background: Ovarian tumours account for 15% to 25% of all primary malignancy and the leading cause of death from gynaecolgical malignancies. There are limited publications related to ovarian tumours from Nepal. Ovarian related surgeries are the common surgeries in Kathmandu University Hospital. This study aims to provide basic information related to ovarian tumours from this geographical region of Nepal. Objectives: To review the nature of ovarian problems and certain socio-demographic information namely: caste, age, address and co-morbid condition of the patients presenting with ovarian problems. Methodology: This is a retrospective study of patients seeking surgical treatment of ovarian lesions in Kathmandu University Hospital from January 1, 2011 to June 30, 2018. This study was undertaken by reviewing the inpatient, outpatients and OT records in the Department of Obstetrics and Gynaecology and the records from Department of Pathology. All the files and computer records were revi...
Histopathological Study of Ovarian Tumors at a Tertiary Care Hospital of Central Nepal
Journal of College of Medical Sciences-Nepal
Background: Ovarian tumors are histogenetically varied and complex tumors spanning all age groups. They account for 30% of all gynaecologic cancers. Malignant tumors carry a high mortality due to its late detection and ineffective screening programs. Current study aims at finding association between age at presentation and size of tumor with behavior of tumors and also association between category of tumor and age at presentation. Methods: This Hospital record based cross-sectional (historical) study was carried out on 158 cases of ovarian tumors received in Department of Pathology, College of Medical Sciences and Teaching Hospital during a time period of five and a half years from January 2012 to June 2017. Results: Age of the patients ranged from 12 to 88 years with maximum cases 96 (60.8%) in 20 – 40 years age group. The mean ±SD of age was 36.6±14.4 years. Majority of the cases 137 (86.7%) were benign. Sixteen (10.1%) cases were malignant and 5 (3.2%) cases were borderline. Majo...
Histopathological pattern of ovarian lesions: a Hospital based study in Batticaloa, Sri Lanka
Journal of Diagnostic Pathology
Ovarian tumours are one of the most common neoplasms encountered in females. A five and a half year retrospective study was carried out in a tertiary care hospital to find out the frequency, age distribution and histopathological spectrum of ovarian lesions. There were 537 ovarian specimens sent for histopathological evaluation either as a solitary specimens or as part of total abdominal hysterectomy (TAH) from January 2012 to June 2017. Benign neoplastic lesions constituted most lesions diagnosed (49%). Among neoplastic ovarian lesions 80.1% cases were benign, 3.7% cases were borderline and 16.2% cases were malignant. Among benign ovarian neoplasms, 43.3% were serous cystadenomas; 30.0% were benign cystic teratomas and 22.4% were mucinous cystadenomas. Majority of malignant neoplasms were serous cystadenocarcinomas(58.5%) followed by mucinous cystadenocarcinoma, clear cell carcinoma, dysgerminoma and germ cell tumour.
International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2017
Background: Ovarian tumors are one of the ubiquitous and common forms of neoplasms in women. The aim of the study was to understand the pattern of benign and malignant ovarian neoplasms and their distribution in different age groups in rural population of India.Methods: A retrospective study conducted in the Department of Pathology in close collaboration with Department of Obstetrics and Gynecology, Dr. Rajendra Prasad Government Medical College, Kangra at Tanda (HP), India. All the patients irrespective of age group who were operated for ovarian neoplasms (benign or malignant) were included in this retrospective analysis over duration of four years (2013 to 2016). “WHO classification system” was used, for classification of all these ovarian tumors. The incidence of these tumors with respect to age group was also studied.Results: During the study period (2013-2016), there were a total of 242 surgeries for ovarian neoplasms. Of these, majority of the tumours were benign 184 (76%), bu...
2020
Methods: 10,799 total women were admitted during the study time. All patients with genital tumours were selected by purposive non probability sampling. Patients with benign tumours were not included. The physical examination, history and study details were collected. Necessary surgical procedures were performed. The tumours were graded clinically, surgically and confirmed histopathologically. Results: The gynaecological cancer incidence in our facilities was 35 (0.32%), in total 10 799. The most common ovarian cancer was 22 (62.86%), then 8 (22.86%) of uterus and 5 (14.29%) of cervix. In the 50-75 age group, ovarian cancer was noted usually, in the 60-75 age group uterine cancer, and cervical cancer in the 40-49 age group. The most common ovarian cancer was serous cystadenocarcinoma, 12 (54.55%); and squamous cell cancer3 (60%), endometrioid adenocarcinoma 6 (75%), were the most common types of cervical and uterine cancer. Gastrointestinal upset, 11 (31%), abdominal distension, 13 (37%), postmenopausal bleeding 11 (31%), vaginal discharge 11 (31%) and irregular vaginal bleeding 9 (26%) were the utmost usual symptoms. Most ovarian cancers were in advanced stage 21 (95.4%), and uterine cancers were diagnosed usually at initial stages 5 (62.5%). Conclusion: The most common gynaecological cancer is ovarian cancer in advanced stages. More thorough study of epidemiology and the screening methods should be carried out effectively to decrease the gynaecological cancer burden and awareness of early symptoms in women.
Pattern of gynaecological malignancies in south western region of Pakistan: An overview of 12 years
Biomedical reports, 2017
Gynaecological malignancies contribute significantly to cancer burden and have a higher rate of mortality and morbidity. The aim of this retrospective study was to determine the pattern of gynaecological malignancies identified between January, 2000 and December, 2011, at the Centre for Nuclear Medicine and Radiotherapy (CENAR). At CENAR 5,072 female patients were registered with different malignancies, of which 632 cases were gynaecological malignancies. Ovarian cancer (47%) was the most common gynaecological malignancy, followed by cervical cancer (29%), uterine cancer (14%), vulvar and vaginal cancer (6%), and gestational trophoblastic neoplasm (4%). Of the ovarian cancer cases, 72.5% had epithelial while 26.5% had non-epithelial cancer. Squamous cell carcinoma was 75.9% in cervix and 87.8% in vulva and vagina while endometrial carcinoma (75.9%) was more frequent in uterus. For gestational trophoblastic neoplasm, 69.2% of patients had choriocarcinoma. Ovarian cancer was the most ...