3-Methyl-5-(4-oxo-4 H -chromen-3-ylmethylene)-1,3-thiazolidine-2,4-dione (original) (raw)

(E)-5-{4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzylidene}thiazolidine-2,4-dione

IUCrData, 2018

In the title compound, C19H18N2O3S, the thiazolidine ring makes dihedral angles of 46.97 (8) and 7.19 (9)° with the pyridine and benzene rings, respectively. The intramolecular structure is stabilized by a weak C—H...S hydrogen bond, which generates a S(6) graph-set motif, and a weak C—H...O contact. In the crystal, N—H...N and C—H...O hydrogen bonds leads to infinite one-dimensional chains along (201) and generate an R 2 2(7) ring-set motif. The crystal structure is further consolidated by weak π–π [centroid-to-centroid distance = 3.8204 (10) Å] interactions.

N -[2-(4-Chlorophenyl)-5-methyl-4-oxo-1,3-thiazolidin-3-yl]pyridine-3-carboxamide

Acta Crystallographica Section E Structure Reports Online, 2011

The title compound, C 16 H 14 ClN 3 O 2 S, crystallizes with two molecules in the asymmetric unit. In the 1,3-thiazolidine rings, the carbonyl O atoms, the S atoms, the methyl groups and the ring carbon attached to the methyl groups are disordered with occupancy ratios of 0.509 (7):0.491 (7) in one molecule and 0.464 (14):0.536 (14) in the other. The crystal structure is stabilized by intermolecular N-HÁ Á ÁN, C-HÁ Á ÁO hydrogen bonds and C-HÁ Á ÁCl interactions. In addition, there is astacking interaction [centroid-centroid distance = 3.794 (3) Å ] between the benzene and pyridine rings. Symmetry codes: (i) x þ 1; y; z; (ii) Àx þ 1; Ày; Àz; (iii) Àx þ 1; Ày þ 1; Àz; (iv) Àx; Ày; Àz þ 1; (v) x À 1; y À 1; z þ 1; (vi) Àx; Ày; Àz.

N-[2-(4-Chlorophenyl)-5-methyl-4-oxo-1,3-thiazolidin-3-yl]pyridine-3-carboxamide

Acta Crystallographica Section E-structure Reports Online, 2011

The title compound, C 16 H 14 ClN 3 O 2 S, crystallizes with two molecules in the asymmetric unit. In the 1,3-thiazolidine rings, the carbonyl O atoms, the S atoms, the methyl groups and the ring carbon attached to the methyl groups are disordered with occupancy ratios of 0.509 (7):0.491 (7) in one molecule and 0.464 (14):0.536 (14) in the other. The crystal structure is stabilized by intermolecular N-HÁ Á ÁN, C-HÁ Á ÁO hydrogen bonds and C-HÁ Á ÁCl interactions. In addition, there is astacking interaction [centroid-centroid distance = 3.794 (3) Å ] between the benzene and pyridine rings. Symmetry codes: (i) x þ 1; y; z; (ii) Àx þ 1; Ày; Àz; (iii) Àx þ 1; Ày þ 1; Àz; (iv) Àx; Ày; Àz þ 1; (v) x À 1; y À 1; z þ 1; (vi) Àx; Ày; Àz.

2-(2,4-Diphenyl-3-azabicyclo[3.3.1]nonan-9-ylidenehydrazono)-1,3-thiazolidin-4-one

Acta Crystallographica Section E Structure Reports Online, 2009

In the title compound, C 23 H 24 N 4 OS, the piperidine and cyclohexane rings adopt twin chair conformations and the phenyl groups occupy equatorial positions. The dihedral angle between the two benzene rings is 10.25 (12). The crystal structure is stabilized by intermolecular N-HÁ Á ÁO hydrogen bonds with the formation of centrosymmetric dimers. Related literature For background on the thiazolidinone system, see: Laurent et al. (2004). For the biological activities of thiazolidinones, see:

3-(2-Methylamino-1,3-thiazol-4-yl)-2H-chromen-2-one

Acta Crystallographica Section E Structure Reports Online, 2012

In the title compound, C13H10N2O2S, the essentially planar 2H-chromene ring system [maximum deviation = 0.0297 (13) Å] and the thiazole ring [maximum deviation = 0.0062 (11) Å] form a dihedral angle of 3.47 (5)°. In the crystal, N—H...N and C—H...O hydrogen bonds link the molecules into two-dimensional networks parallel to thebcplane. C—H...π and π–π [centroid–centroid separation = 3.6796 (8) Å] interactions further stabilize the crystal structure.

3-(2-Methylamino-1,3-thiazol-4-yl)-2H-chromen-2-one

Acta Crystallographica Section E-structure Reports Online, 2012

In the title compound, C 13 H 10 N 2 O 2 S, the essentially planar 2H-chromene ring system [maximum deviation = 0.0297 (13) Å ] and the thiazole ring [maximum deviation = 0.0062 (11) Å ] form a dihedral angle of 3.47 (5). In the crystal, N-HÁ Á ÁN and C-HÁ Á ÁO hydrogen bonds link the molecules into two-dimensional networks parallel to the bc plane. C-HÁ Á Á and-[centroid-centroid separation = 3.6796 (8) Å ] interactions further stabilize the crystal structure.