Clinical Trial End Points for Hemodialysis Vascular Access: Background, Rationale, and Definitions (original) (raw)

This manuscript introduces a four-paper series aimed at establishing consensus on clinical trial end points for hemodialysis vascular access, addressing a critical barrier to innovation in treatment options. Highlighting the poor patency rates and complications associated with current vascular access methods, the paper emphasizes the role of the Kidney Health Initiative in promoting collaboration among stakeholders to refine product development pathways. Ultimately, the goal is to enhance patient outcomes through the development of effective therapies.