Evaluation of symptoms and symptom combinations in histamine intolerance (original) (raw)

is challenging and the symptoms may occur according to the known 4 receptors of histamine. 3 Here, we describe various symptoms and complex symptom combinations in patients with HIT. This may help to clinically recognize and diagnose histamine intolerance. METHODS In a retrospective analysis of outpatients' charts, we identified 133 patients (male:female, 30:103; median age, 39 years; age range, 18-81 years), who presented with recurring functional nonspecific abdominal complaints and who had a DAO value < 10 U/mL (median, 5.8 U/mL; range, 1.5-9.9 U/mL). In our outpatient setting we decided to include serum DAO determination in the evaluation of patients who present with recurring functional nonspecific abdominal complaints. 4 A thorough