On the Long-Range Charge Transfer in DNA (original) (raw)

The sequence dependence of charge transport through stacked Watson-Crick base pairs was analyzed for coherent hole motion interrupted by a temporary charge localization on guanine bases. The relative rate of hole transfer to the GGG sequence has been expressed in terms of the frequency of jumps through adeninethymine base pairs separating adjacent guanine sites. The obtained expression yields practically the same sequence dependence as measurements, without invoking adjustable parameters. For alternating adeninethymine/guanine-cytosine sequences, our analysis predicts that the relative charge-transfer rate varies in inverse proportion to the sequence length at short distances, with change to the slow exponential decay at longer distances.