Severity of Autonomic and Sensory Neuropathy and the Impairment of Visual-and Auditory-Evoked Potentials in Type 1 Diabetes (original) (raw)
2006, Diabetes …
It became clear in the last decades that neuropathy is not a separate clinical entity, but a component of several re-lated complications (1). Although the functional consequences of neuropathy are well defined in various organ systems, the relationship of the alterations in the networks of ...
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Differences and Similarities in Neuropathy in Type 1 and 2 Diabetes: A Systematic Review
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Background: Diabetic neuropathy is defined as the dysfunction of the peripheral nervous system in diabetic patients. It is considered a microvascular complication of diabetes mellitus. Its presence is associated with increased morbidity and mortality. Although several studies have found alterations at somatic motor, sensory levels and at the level of autonomic nervous system in diabetic patients, there is not a systematic approach regarding the differences in neuropathy between the major variants of diabetes, e.g., type 1 and 2 diabetes at both neurological and molecular level. Data sources: we systematically (Medline, Scopus, and Cochrane databases) evaluated the literature related to the difference of neuropathy in type 1 and 2 diabetes, differences in molecular biomarkers. Study characteristics: seventeen articles were selected based on pre-defined eligibility criteria. Conclusions: both superficial sensitivity (primarily thermal sensitivity to cold) and deep sensitivity (such as...
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