Analysis of Immunization Problems in Prevention of Diphtheria (original) (raw)

Analysis Factors Affecting Diphtheria Epidemic in Bangkalan Madura

2016

Introduction: Diphtheria is a disease caused by Corynebacterium diphtheriae. in 2012 this disease became epidemic in several regions of East Java, including Bangkalan, Situbondo, Jombang and Surabaya. Method: This study was an applied research using secondary data drawn from Puskesmas Bangkalan in 2013. Results: The results showed that the human resources versus the target number PIN (p = 0.048) and immunization coverage have a relationship with the incidence of diphtheria in Bangkalan (p = 0.041). Discussion: High immunization coverage is expected to reduce the incidence of the disease are immunized. The full immunization coverage have a significant influence on the case of diphtheria. The results of this study are expected in improving health promotion in order to reduce cases of diphtheria in East Java Key word : dihtheria, epidemic

Determinant factors for giving the diphtheria, pertussis, and tetanus immunization in West Java Province 2017

Berita Kedokteran Masyarakat

Purpose: DPT-HB immunization is one of the mandatory basic immunizations given to children to prevent diphtheria, pertussis (whooping cough) and tetanus. In 2017, West Java was one of the provinces that reported Diphtheria Outbreaks with 14 deaths from 153 cases. This study aims to determine the relationship of parental education, area of residence, visits to health care facilities and insurance ownership of the provision of DPT-HB Immunization in children in West Java Province.Method: The study design was cross sectional. The sample in this study was based on secondary children record data of the 2018 IDHS consisting of DPT-HB/Pentavalent immunization; parental education; residential area; visits to health care facilities and ownership of health insurance.Results: The results of this study were obtained between parental education (p value: 0,0001, OR: 2,084) and the area of residence (p value: 0,028, OR: 0,637) having a relationship with DPT-HB / Pentavalent immunization.Conclusion...

Implementation of Control Policy of Diphtheria Outbreak and Outbreak Response Immunization (Ori) in Kota Depok, 2017

2019

Diphtheria is a contributor to an outbreak (KLB) for some regions in Indonesia, included West Java Province. Diphtheria cases had increased through 2015 - 2016, the cases increased from 59 cases to 153 cases. Depok City became one of the contributors of diphtheria cases that have fluctuating incidents. Disease trends have decreased in 2013-2015 but then increased in 2016 to 8 cases. This study discusses policy implementation, viewed from policy sources, resource arrangements, the characteristics of implementing agencies, bureaucratic structures, communications, the influence of dispositions and socio-economic and political circumstances in control of Diphtheria Outbreak and Outbreak Response Immunization (ORI) in Depok City in 2017. This type of research is qualitative research with descriptive design, through in-depth interviews and document review. The results showed that the limited resources, especially human resources, the lack of cross-sectoral concern and social environment f...

Correlation between immunization status and pediatric diphtheria patients outcomes in the Sampang District, 2011-2015

Paediatrica Indonesiana, 2018

Background The number of diphtheria cases recently increased, such that an outbreak was declared in East Java Province, which includes the Sampang District. Immunization completion status is a determining factor for diptheria infection. Objective To investigate for correlations between immunization status and outcomes (severity level, fatality, and complications) of diphtheria patients in the Sampang District. Methods This analytic, cross-sectional study used secondary data from the East Java Provincial Health Office on diphteria patients aged 0-20 years during the 2011-2015 outbreak in the Sampang District and interviews with diphtheria patients in that region. The Diphtheria Research Team of Dr. Soetomo Hospital collected data on immunization status, diphtheria severity (mild, moderate, or severe), case fatality (died or survived), and complications in the patients (with or without complications). Spearman's, Chi-square, and Fisher's exact tests were used for data analyses, accordingly. Results Seventy-one patients with clinical diphtheria were identified, 17 of whom were confirmed with positive culture results. The case fatality rates were 7% in patients with clinical and 5.9% in confirmed diphtheria. There were no correlations between patient immunization status and severity (P=0.469 clinical, P=0.610 confirmed), or fatality (P=0.618 clinical, P=0.294 confirmed) of diphtheria in the clinical and confirmed diphtheria patients. However, there was a correlation between patient immunization status and the emergence of complications in clinical (P=0.013), but not in confirmed (P=0.620) diphtheria patients. Conclusion There is a correlation between immunization status and complications in clinical diphtheria patients. Such a correlation is not found in confirmed diphtheria cases because none of the patients had complete immunization status.

EPIDEMIOLOGY OF DIPHTHERIA IN PURWAKARTA REGENCY, INDONESIA

EPIDEMIOLOGY OF DIPHTHERIA IN PURWAKARTA REGENCY, INDONESIA, 2019

Background: Diphtheria is considered as a neglected disease since it was successfully eliminated in many countries. However, there were several sporadic reemergence cases of Diphtheria and the peak was outbreak in Indonesia in 2017. This research was a descriptive study aimed to explore epidemiology of diphtheria by person, time and place in one of diphtheria endemic area. Methods: This was a descriptive study with cross sectional design in Purwakarta Regency, West Java, Indonesia in 2018. Several data were collected in this study such as diphtheria cases by age, time of occurrence, gender, place and immunization status. The data was collected from Purwakarta Health Office. It was the data from the year of 2015-2017. The data was analysed by using descriptive analysis with percentages displayed in graphs and tables. Results: This study reveals that Purwakarta regency is an endemic area of diphtheria with fluctuated cases since 2015-2017. More cases of diphtheria occurred from September to December in rainy season. More cases suffered by children in 5-9 years old, however, this disease also infected adult population. The area with high diphtheria cases in this study also areas with high population densities which is conducive for C diphteriae transmission. Low coverage of immunization is highlighted in the result of this study, which could explain why diphtheria cases occurred continuously in this area. Conclusions: High number of diphtherias in this area should be an awareness for local health officer to do an effective preventive effort such as increasing the coverage of vaccination. Furthermore, optimizing the role of religious and community leader should be made to support diphtheria vaccination programs.

Impact of a three-dose diphtheria outbreak response immunization in East Java, Indonesia, 6 months after completion

Human Vaccines & Immunotherapeutics

Several outbreaks of diphtheria have occured in the East Java Province of Indonesia since 2011. The last effort to stop the outbreak in the province was a three round outbreak response immunization (ORI) in 2018.The aim of the this study was to evaluate the impact of the 2018 ORI in East Java province-6 months following the completion of the program. Surveillance data was collected for 6 month period, from January to June 2019. The source of data was the district health offices, hospitals, community health centers, and private physician and paramedic practices. The data included demographic characteristics, involved health facilities, patient immunization history, clinical signs and symptoms, some laboratory test results and other additional examinations. All cases were evaluated by the East Java Provincial Diphtheria Expert Committee and not based on the individual physician decision. During the 6 month period, there were 97 diphtheria cases which approved by the Diphtheria Expert Committee. The reports came from 36 of 38 districts. One patient died, denoting a case fatality rate of 1%. The majority were 19 years of age or less, with uncomplete immunization. Patients above 19 years were 24%. Compared with 2017 (438 cases) and 2018 (310), 2019 saw a significant reduction in the number of reported cases. Only 4 positive culture results were collected (positivity rate 4,13%). Two patients had Mitis subtype and the other two had Gravis subtype. Diphtheria ORI in East Java had a significant impact during the first 6 months of 2019.

The Mapping and Analysis of Diphtheria Cases in Surabaya (2017-2018)

2021

Diphtheria is an acute disease that attacks the airways and causes deaths. The risk factors for diphtheria are low Diphtheria-Pertussis-Tetanus (DPT) immunization coverage and an unhealthy home environment. One effort to control diphtheria is by providing information in the form of the patient's location that makes it easier to determine the target group of people intervened. The city of Surabaya experienced an increase of 50 diphtheria cases from 2017 to 2018. This study aimed to map and analyze diphtheria cases based on DPT immunization and healthy homes from 2017 to 2018 in the city of Surabaya. This study was classified descriptive analytic and used an ecological design. This study used the Pearson's correlation coefficient statistical test to analyze secondary data from the Surabaya City’s Health Profile of 2017 to 2018. This study employed the Health Mapper 4.3.0.0 application and SPSS software version 23. The study variables were diphtheria cases, DPT immunization cov...

Association for Percentage of DPT Immunization Against Incidence of Diphtheria in West Java province 2017 with spatial analysis

2019

Diphtheria is one of the infectious diseases that can be prevented by immunization which was still suffered 954 people with a mortality rate of 4.61%. West Java Province is one of the provinces with the second largest number of sufferers in Indonesia. Many statistical tests but do not include spatial elements in the analysis. The purpose of this study was to find out the spatial relationship between diphtheria incidence and the relationship factors in DPT immunization coverage. This study was cross-sectional with spatial regression data analysis approach were used 2017 of West Java Province health profile’s data and reports from the Central Statistics Agency of Indonesia. The results of analysis in the form of spatial patterns were interpreted. This study was Moran’s Index of diphtheria in West Java Province was 0.255. Diphtheria in West Java Province was collecting pattern in west of the region and autocorrelation between district / cities. The low percentage of immunizations in Ci...