Potent and Orally Active Small-Molecule Inhibitors of the MDM2− p53 Interaction (original) (raw)

Cell Cycle, 2010

Small-Molecule Inhibitors of p53-MDM2 Interaction: the 2006-2010 Update

Current Pharmaceutical Design, 2011

Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy

shafiq Ahmed

Annual Review of Pharmacology and Toxicology, 2009

View PDFchevron_right

Non peptidic small molecular inhibitors of the p53-MDM2 interaction

Chirag kumar J. Gohil, IP Innovative Publication Pvt. Ltd.

IP innovative publication pvt ltd, 2019

View PDFchevron_right

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

Denzil Bernard

Proceedings of the National Academy of Sciences, 2008

View PDFchevron_right

Insilico designing and development of potent drug inhibitor to MDM2 protein in cancer through molecular docking studies

Manas Ranjan

View PDFchevron_right

p53-Mdm2 Interaction Inhibitors as Novel Nongenotoxic Anticancer Agents

harish chopra

Current Cancer Drug Targets, 2018

View PDFchevron_right

Design, synthesis and in vitro and in vivo antitumour activity of 3-benzylideneindolin-2-one derivatives, a novel class of small-molecule inhibitors of the MDM2-p53 interaction

MOHD ADIL

View PDFchevron_right

Small Molecule Antagonists of the MDM2 Oncoprotein as Anticancer Agents

James Addo

Current Cancer Drug Targets, 2005

View PDFchevron_right

Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapeutics

hadjer hamadou

Topics in Medicinal Chemistry, 2012

View PDFchevron_right

Targeting the MDM2-p53 Interaction for Cancer Therapy

Kalkunte Srivenugopal

Clinical Cancer Research, 2008

View PDFchevron_right

Molecular Modeling Approaches in the Discovery of New Drugs for Anti-Cancer Therapy: The Investigation of p53MDM2 Interaction and its Inhibition by Small Molecules

Antonino Lauria

Current Medicinal Chemistry, 2010

View PDFchevron_right

Discovery of a new small-molecule inhibitor of p53–MDM2 interaction using a yeast-based approach

Alessandra Bisio, Yari Ciribilli, Alberto Inga

Biochemical Pharmacology, 2013

View PDFchevron_right

Targeting dysregulation signatures of p53-MDM2 interactions to identify newer small molecule inhibitors for cancer therapy: Insight from computational direction

Haruna umar

2021

View PDFchevron_right

SAR405838: an optimized inhibitor of MDM2-p53 interaction that induces complete and durable tumor regression

Denzil Bernard

Cancer research, 2014

View PDFchevron_right

Rational Design and Binding Mode Duality of MDM2–p53 Inhibitors

Michael Bartberger

Journal of Medicinal Chemistry, 2013

View PDFchevron_right

Anticancer strategies by upregulating p53 through inhibition of its ubiquitination by MDM2

Abiodun Anifowose

Medicinal Chemistry Research, 2020

View PDFchevron_right

Improving colon cancer therapy with a new promising small-molecule activator of the p53-pathway through disruption of p53-MDM2/MDMX interactions

Liliana Raimundo

Proceedings of 5th International Electronic Conference on Medicinal Chemistry, 2019

View PDFchevron_right

Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: Implications for therapy

Kathryn Packman, O. Myklebost

Proceedings of the National Academy of Sciences, 2006

View PDFchevron_right

Discovery of AMG 232, a Potent, Selective, and Orally Bioavailable MDM2–p53 Inhibitor in Clinical Development

Michael Bartberger

Journal of Medicinal Chemistry, 2014

View PDFchevron_right

On the Mechanism of Action of SJ-172550 in Inhibiting the Interaction of MDM4 and p53

Artur Pirog, Grzegorz Dubin

PLoS ONE, 2012

View PDFchevron_right

DIMP53-1: a novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer properties

Sara Gomes

Molecular Oncology, 2017

View PDFchevron_right

Identification of new inhibitors of Mdm2–p53 interaction via pharmacophore and structure-based virtual screening

Sara Rawashdeh

Drug Design, Development and Therapy

View PDFchevron_right

Potent and Orally Active Small-Molecule Inhibitors of the MDM2− p53 Interaction (original) (raw)

Related papers