Abstract 16882: Prescribed Flow in 3D Printed Models for Determination of Coronary Ischemia: A Comparison to a Computational Fluid Dynamic-based Assessment (original) (raw)

2016

Abstract

Introduction: Advances in coronary computed tomography angiography (CCTA) imaging and 3D printing have enabled fabrication of physical models of coronary arterial geometry. Computational fluid dynamics (CFD) applied to CCTA allows determination of fractional flow reserve—or the hyperemic pressure ratio (P d /P a ) across a stenosis from a typically acquired CT (FFR CT ), and has been demonstrated to be a non-invasive “gold standard” for determining ischemia. We evaluated the influence of prescribed flow rates on P d /P a by 3D printed models compared to CFD evaluation. Methods: Prescribed flows were evaluated using an in vitro experimental flow loop with a pump circulating blood analog fluid at steady-state flow (Fig 1A). A 50% diameter stenosis (DS) model with a smooth Gaussian shape was fabricated using VeroClear rigid material in an Objet260 Connex printer. Mean proximal pressure (P a ) was maintained at 90 mm Hg using a linear flow needle valve. P d /P a at differing prescribed ...

Kranthi Kolli hasn't uploaded this paper.

Let Kranthi know you want this paper to be uploaded.

Ask for this paper to be uploaded.