Monoclonal antibodies recognize conformational alterations leading to decreased bioactivity of human growth hormone (original) (raw)

The recognition by monoclonal antibodies of various portions of a major antigenic site of human growth hormone

Pierre Masson

Molecular Immunology, 1982

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Allosteric effects of monoclonal antibodies on human growth hormone

L. Roguin

Molecular and Cellular Biochemistry, 1994

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Evidence from the use of monoclonal antibody probes for structural heterogeneity of the growth hormone receptor

Ross Barnard

Biochemical Journal, 1985

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Functional characterization of monoclonal antibodies specific to growth hormone receptor

Roberta Galbo

Molecular Immunology, 1996

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Monoclonal Antibody Against Human Growth Hormone Receptor

Claudia Casnici

Hybridoma, 2000

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Characterization of the growth hormone-binding protein of human serum using a panel of monoclonal antibodies

Ross Barnard

Journal of Endocrinology, 1989

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Enhancement of growth hormone activity in vivo by monoclonal antibodies: potential for autoimmunization

Peter Bates

Proceedings of the Nutrition Society, 1988

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An antigenic determinant common to human chorionic somatomammotropin and human growth hormone revealed by limited proteolysis of immune complexes

Mauro Rustici

Biopolymers, 1991

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Inhibitory effect of growth-enhancing antibody on the interaction between growth hormone and growth hormone binding protein

Bosco Wang

Molecular and Cellular Endocrinology, 1993

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Positive cooperative effects between receptors induced by an anti-human growth hormone allosteric monoclonal antibody

Viviana Blank

Life Sciences, 2000

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Human growth hormone-variant demonstrates a receptor binding profile distinct from that of normal pituitary growth hormone

Nancy Cooke

The Journal of biological chemistry, 1990

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Specific monoclonal antibodies and ultrasensitive immunoassays for 20K and 22K human growth hormone

Christian Strasburger

Growth Hormone & IGF Research, 2010

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Activation of Chimeric and Full-length Growth Hormone Receptors by Growth Hormone Receptor Monoclonal Antibodies

Zida Wu

Journal of Biological Chemistry, 1998

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The Molecular Properties of Human Growth Hormone

Salvatore Aloj

Journal of Biological Chemistry, 1972

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Quantification of antibodies to human growth hormone by high-performance protein G affinity chromatography with fluorescence detection

Richard Sportsman

Analytical Chemistry, 1991

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Human multiple organ-reactive monoclonal autoantibody recognizes growth hormone and a 35,000-molecular weight protein

Jo Satoh, K. Essani

Journal of Clinical Investigation, 1984

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ELISA for Determination of Human Growth Hormone: Recognition of Helix 4 Epitopes

Juliana Moura

Journal of Biomedicine and Biotechnology, 2004

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5 Recombinant human growth hormone

Linda Fryklund

Clinics in Endocrinology and Metabolism, 1986

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Conformational Changes Required in the Human Growth Hormone Receptor for Growth Hormone Signaling

Mario Mellado

Journal of Biological Chemistry, 1997

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Growth Hormone Immunoreactivity Does Not Reflect Bioactivity

M. Bozzola

Pediatric Research, 2000

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A Novel Specific Bioassay for Serum Human Growth Hormone

Noriyuki Katsumata

The Journal of Clinical Endocrinology & Metabolism, 2000

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Antibody-coated tube method for radioimmunoassay of human growth hormone

Geoffrey Tregear

Clinica Chimica Acta, 1970

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Development of a polyclonal antiserum for the detection of the isoforms of the receptors for human growth hormone-releasing hormone on tumors

Judit Horvath

Proceedings of the National Academy of Sciences, 2004

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Evidence for two distinct classes of high affinity growth hormone binding proteins in pregnant rat serum

Adrian Herington

Growth Hormone & Igf Research - GROWTH HORM IGF RES, 2000

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Evidence for Involvement of the Carboxy Terminus of Helix 1 of Growth Hormone in Receptor Binding: Use of Charge Reversal Mutagenesis to Account for Calcium Dependence of Binding and for Design of Higher Affinity Analogs

Ross Barnard

Biochemistry, 1994

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Growth hormone (GH) assays: influence of standard preparations, GH isoforms, assay characteristics, and GH-binding protein

Kerstin Albertsson-wikland

Clinical chemistry, 1997

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Growth hormone isoforms and segments/fragments: Molecular structure and laboratory measurement

Paolo Spinella, Rosalba Gatti

Clinica Chimica Acta, 2006

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Evidence for Involvement of the Carboxy Terminus of Helix 1 of Growth Hormone In Receptor Binding: Use of Charge Reversal Mutagenesis to Account for Calcium …

Michael Waters, Ross Barnard

Biochemistry, 1994

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The serum growth hormone binding protein: pregnant with possibilities

Ross Barnard

Journal of Endocrinology, 1997

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A monoclonal antibody recognizing an epitope shared by receptors for growth hormone, prolactin, interleukin 2 and interleukin 6

Silvia Longhi

Molecular and Cellular Biochemistry, 1999

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A Polymorphism in the Growth Hormone (GH)-Releasing Hormone (GHRH) Receptor Gene Is Associated with Elevated Response to GHRH by Human Pituitary Somatotrophinomas in Vitro

David Poyner

Biochemical and Biophysical Research Communications, 2000

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A rapid method for the preparation of 1251-labelled human growth hormone for receptor studies, using reverse-phase high performance liquid chromatography

Mapoko ILONDO

Biochemical and Biophysical Research Communications, 1986

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Time-resolved immunofluorometric assay (tr IFMA) of human growth hormone

Kerstin Albertsson-wikland

Clinical Chemistry

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Synthetic peptides and monoclonal antibodies of predetermined specificity in the study of human chorionic gonadotropin

Mehmet Ozturk

International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology, 1987

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