Biological activities of phenolic compounds extracted from flaxseed meal (original) (raw)
Bulletin of the National Research Centre
Background There is a worldwide demand for phenolic compounds (PC) because they exhibit several biological activities. The present investigation deals with a comprehensive study on the biological activities of phenolic compounds extracted from flaxseed meal (FM) with the aid of ultrasonic waves. Results The antioxidant activity of the PC extract of FM is considerably high when measuring it by the three methods (the β-carotene coupled oxidation method, the DPPH free radical scavenging activity method, and measuring the reducing antioxidant power). The toxicity test revealed that the PC extract was nontoxic on normal retina cell line. Also, it has no anticoagulating activity. Evaluation of antimicrobial activity showed that it is effective towards four strains only from seven. FM phenolic extract has been evaluated as chemo-preventive agents by testing the product for any cytotoxic activity against human tumor cell lines. The highest inhibitory effect was achieved on cell lines of col...
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ANTIOXIDANT ACTIVITY OF ETHANOLIC EXTRACTS OF FLAXSEED IN A ?-CAROTENE-LINOLEATE MODEL SYSTEM
Journal of Food Lipids, 1993
Flaxseed meal was extracted with 95% ethanol at 80C. The extract was separated on a Sephadex LH-20 column using methanol as eluate. Four major fractions according to their absorbances at 280 nm were separated. The antioxidant effect of these fractions in a β-carotene-linoleate system indicated that fraction I was most active. Absorption maximum for UV spectrum of this fraction was 290 nm and TLC analysis indicated the presence of 4 phenolic compounds in it. Fractions II to IV showed a very low antioxidant activity.
Flaxseed Cake-A Sustainable Source of Antioxidant and Antibacterial Extracts
2014
Flaxseed cake, a by-product of the oil cold pressing technology, was subjected to extraction and acidic hydrolysis to obtain extracts rich in polyphenols and especially in lignans. The second step was to assess the extracts in order to evaluate their potential to be used as additives in the food and cosmetics industries. The identification and quantification of secoisolariciresinol (SECO), matairesinol (MATA) and lariciresinol (LARI) in the said extracts was accomplished using the HPLC method. The total polyphenol content, radical scavenging activity and antimicrobial activity were determined. The total polyphenol content for the samples extracted with 60% ethanol, hydrolyzed at 80 °C, was comparable to that of the extracts obtained from spices or medicinal plants. The radical scavenging ability of the extract correlates well with the total polyphenol content and is comparable to that of common synthetic phenolic antioxidants used in foods and cosmetics. Flaxseed cake extracts also ...
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