Peripheral plasma testosterone levels in hypothyroid-induced male goats (original) (raw)

Gupta, P.S.P., Sanwal, P.C. and Varshney, V.P., 1991. Peripheral plasma testosterone levels in hypothyroid-induced male goats. Small Rumin. Res., Hypothyroidism was induced in four male goats by subcutaneous injection of thiourea at 100 mg/ kg body weight per day for 15 days and at 66.7 mg/kg per day for the next 15 days. Hypothyroidism was confirmed by significant (P< 0.001 ) reductions in triiodothyronine and thyroxine levels. Plasma testosterone levels in thiourea-treated goats were significantly (P< 0.05) lower than in control animals during the entire treatment period. Plasma testosterone during the first 20 days of treatment fluctuated between 0.21 and 1.04 ng/ml (i.e. 10-52% of the pretreatment level) in thiourea-treated animals. During the last 10 days of treatment, testosterone fluctuated at 0.1-0.23 ng/ml, less than 12% of the pretreatment level. The influence of thyroid status on plasma testosterone in male goats has been demonstrated by this experiment; the results may be important for more efficient use of breeding animals.