A Study on Solute Dispersion in a Three Layer Blood-like Liquid Flowing through a Rigid Artery (original) (raw)

Nonlinear Analysis for Shear Augmented Dispersion of Solutes in Blood Flow through Narrow Arteries

Journal of Applied Mathematics, 2012

The shear augmented dispersion of solutes in blood flow (i) through circular tube and (ii) between parallel flat plates is analyzed mathematically, treating blood as Herschel-Bulkley fluid model. The resulting system of nonlinear differential equations are solved with the appropriate boundary conditions, and the expressions for normalized velocity, concentration of the fluid in the core region and outer region, flow rate, and effective axial diffusivity are obtained. It is found that the normalized velocity of blood, relative diffusivity, and axial diffusivity of solutes are higher when blood is modeled by Herschel-Bulkley fluid rather than by Casson fluid model. It is also noted that the normalized velocity, relative diffusivity, and axial diffusivity of solutes are higher when blood flows through circular tube than when it flows between parallel flat plates.

Unsteady solute dispersion in blood rheology with reversible phase exchange at the artery wall

International Journal of Engineering & Technology

The effect of reversible phase exchange between the flowing fluid and wall tissues of arteries in the unsteady dispersion of solute in blood flow through a narrow artery is analysed mathematically, modelling the blood as Casson fluid. The resulting convective diffusion equation along with the initial and boundary conditions is solved analytically using the derivative series expansion method. The expressions for the negative asymptotic phase exchange, negative asymptotic convection, longitudinal diffusion coefficient and mean concentration are obtained. It is noted that when the solute disperses in blood flow through a narrow artery, the negative exchange coefficient, the negative convection coefficient increase and the longitudinal diffusion coefficient decreases with the increase of the Damköhler number and partition coefficient.

Mathematical Modeling of Unsteady Solute Dispersion in Bingham Fluid Model of Blood Flow Through an Overlapping Stenosed Artery

Journal of Advanced Research in Fluid Mechanics and Thermal Sciences, 2021

An artery narrowing referred to as atherosclerosis or stenosis causes a reduction in the diameter of the artery. When blood flow through an artery consists of stenosis, the issue of solute dispersion is more challenging to solve. A mathematical model is developed to examine the unsteady solute dispersion in an overlapping stenosed artery portraying blood as Bingham fluid model. The governing of the momentum equation and the constitutive equation is solved analytically. The generalized dispersion model is imposed to solve the convective-diffusion equation and to describe the entire dispersion process. The dispersion function at steady-state decreases at the center of an artery as the stenosis height increase. A reverse behavior is shown at an unsteady-state. As the plug core radius, time and stenosis height increase, the dispersion function decreases at the center of an artery. There is a high amount of red blood cells at the center of the artery but no influences near the wall. Henc...

Effect of boundary absorption on dispersion in Casson fluid flow in an annulus: application to catheterized artery

Acta Mechanica, 2009

The combined effect of annular gap, yield stress and irreversible boundary reaction on the dispersion process in a Casson fluid flow is studied using generalized dispersion model. The study describes the development of dispersive transport following the injection of a tracer in terms of the three effective transport coefficients viz. absorption, convection and dispersion coefficients. The combined effect of annular gap, yield stress and wall absorption parameter on the above three effective transport coefficients is discussed. It is observed that the absorption coefficient is independent of the yield stress of the fluid and depends on the annular gap and wall absorption parameter. It is also observed that the asymptotic convection, dispersion coefficients are dependent on the yield stress of the fluid, annular gap and wall absorption parameter. The effect of the flow parameters on the mean concentration is studied. Application of this model for understanding the dispersion of solute in blood in a catheterized artery is discussed.

On Dispersion of a Reactive Solute in a Pulsatile Flow of a Two-Fluid Model

Journal of Applied Fluid Mechanics

The present paper is a study on dispersion of reactive solute in an oscillatory flow of a two-fluid, three-layer Casson-Newtonian continuum using Aris-Barton's approach. A two-fluid model of blood flow has been considered, the fluid in the central region is taken to be a Casson fluid (a core of red blood cell suspension) and a peripheral layer of plasma modelled as Newtonian fluid. The governing equations for the velocity distribution have been solved using a perturbation technique, and the effective dispersion coefficient has been evaluated numerically (FDM) by solving the moment equations. Using the Hermite polynomial representation of central moments the axial distribution of mean concentration is determined. The main objective is to look into the impact of yield stress, peripheral layer thickness, irreversible and reversible reaction rate on the dispersion process. The study has significant applications on the transport of species in a blood flow system.

Herschel-Bulkley Model of Blood Flow through a Stenosed Artery with the Effect of Chemical Reaction on Solute Dispersion

Malaysian Journal of Fundamental and Applied Sciences, 2021

A non-Newtonian mathematical model of blood described as a Hershel-Bulkley fluid model flowing in a stenosed artery with the effect of a chemical reaction is mathematically studied. The expressions of the shear stress, mean velocity and absolute velocity in the plug and non-plug flow field are evaluated analytically. The convective-diffusion equation is solved using the Taylor-Aris technique subject to the relevant boundary constraint in determining the concentration, relative and effective axial diffusivity. The efficiency of the dispersion process is affected by the presence of chemical reaction and stenosis in blood flow. The normalized velocity decreases as stenosis height and stenosis length increase. The relative axial diffusivity is significantly lower while the effective axial diffusivity decreases considerably as the chemical reaction rate, the height of the stenosis and the length of the stenosis increase. Besides, it is observed that as the solute disperses in the presenc...

Dispersion of a solute in pulsatile non-Newtonian fluid flow through a tube

Acta Mechanica, 2012

The unsteady dispersion of a solute by an imposed pulsatile pressure gradient in a tube is studied by modeling the flowing fluid as a Casson fluid. The generalized dispersion model is applied to study the dispersion process, and according to this process, the entire dispersion process is expressed in terms of two coefficients, the convection and the dispersion coefficients. This model mainly brings out the effects of yield stress and flow pulsatility on the dispersion process. It is observed that the dispersion phenomenon in the pulsatile flow inherently differs from the steady flow, which is due to a change in the plug flow radius during a cycle of oscillation. Also, it was found that the dispersion coefficient fluctuates due to the oscillatory nature of the velocity. It is seen that the dispersion coefficient changes cyclically, and the amplitude and magnitude of the dispersion coefficient increases initially with time and reaches a non-transient state after a certain critical time. It is also seen that this critical time varies with Womersley frequency parameter and Schmidt number and is independent of yield stress and fluctuating pressure component. It is observed that the yield stress and Womersley frequency parameter inhibit the dispersion of a solute. It is also observed that the dispersion coefficient decreased approximately 4 times as the Womersley frequency parameter increases from 0.5 to 1. The study can be used in the understanding of the dispersion process in the cardiovascular system and blood oxygenators.

Effect of body acceleration on dispersion of solutes in blood flow

Acta mechanica, 2011

The unsteady dispersion of a solute in blood flow modeling blood as a Newtonian fluid under the influence of a body acceleration is studied using the generalized dispersion model proposed by Gill and Sankarasubramanian . As a result, the total process of dispersion can be described in terms of a simple diffusion process with the effective diffusion coefficient as a function of time. The model brings out mainly the effect of body acceleration and radius of the artery on the overall dispersion process. In the absence of body acceleration, the dispersion coefficient is found to increase rapidly and maintains a steady value in aorta while in other arteries it oscillates about a mean value after reaching it. Body acceleration is observed to enhance the value of the dispersion coefficient in all arteries. The effective diffusivity is found to depend on body acceleration. In the presence of body acceleration, it is noticed that there is a decrease in the effective diffusivity in aorta, femoral, and carotid while in coronary it is increased.

Hydrodynamic Dispersion of Solute under Homogeneous and Heterogeneous Reactions

International Journal of Heat and Technology, 2019

The present investigation deals with Taylor dispersion of reactive species in Casson liquid in an oscillatory flow because of the pulsatile pressure gradient. The solute is considered to be chemically active at the boundary and also participate a first order reaction within the bulk flow. To evaluate transport coefficients, Aris-Barton moment technique is considered. The solute transport process is discoursed in detailed with respect to yield stress, chemical reaction parameter, Womersly number etc. The study reveals that both wall absorption and bulk flow reaction have a significant response on dispersion phenomena. Both the chemical reactions agree to diminish the negative exchange coefficient and the apparent dispersion coefficient, however, increases the negative convection coefficient. The negative exchange coefficient is independent of yield stress but a significant variation is observed due to yield stress in the cases of negative convection coefficient and the apparent dispersion coefficient. The axial distribution of mean concentration is approximated by using the Hermite polynomial representation of central moments as a function of reaction rate parameters, wall absorbing parameter, yield stress etc. The present article may be useful for the studies related to physiological blood flow analysis.

Exact analysis of unsteady convective diffusion in Casson fluid flow in an annulus – Application to catheterized artery

Acta Mechanica, 2006

The dispersion of a solute in the flow of a Casson fluid in an annulus is studied. The generalized dispersion model is employed to study the dispersion process. The effective diffusion coefficient, which describes the whole dispersion process in terms of a simple diffusion process, is obtained as a function of time, in addition to its dependence on the yield stress of the fluid and on the annular gap between the two cylinders. It is observed that the dispersion coefficient changes very rapidly for small values of time and becomes essentially constant as time takes large values. In non–Newtonian fluids the steady state is reached at earlier instants of time when compared to the Newtonian case and the time taken to reach the steady state is seen to depend on the values of the yield stress. It is observed that a decrease in the annular gap inhibits the dispersion process for all times both in Newtonian as well as in non–Newtonian fluids. When the yield stress is 0.05, depending upon the size of the annular gap (0.9–0.7) the reduction factor in the dispersion coefficient varies in the range 0.58–0.08. The application of this study for understanding the dispersion of an indicator in a catheterized artery is discussed.