Citation: Ahmeti I, Simonovska L, Krstevska B, Ristevska N. Fine Needle Aspiration in Thyroid Nodules -One Year Experience (original) (raw)
Related papers
Fine Needle Aspiration in Thyroid Nodules - One Year Experience
Open Access Macedonian Journal of Medical Sciences, 2015
AIM: To estimate suspect nodule for benign or malignant characteristics, and to verify cytological features of the node with the fine needle aspiration (FNA) under ultrasound.DESIGN: A total of 106 patients were analyzed. FNA biopsy was performed at outpatient clinic via ultrasound. Inform consent was signed for each patient. Preparation of procedure with local anaesthesia was made by assistant nurse.PROCEDURE: Parallel approach of ultrasound guided fine needle aspiration (USGFNA) was used for each patient. This approach allows the operator to observe needle penetration, location and pathway of the entire needle within the neck, thyroid and nodule, which remain visible on the monitor. As a side effect commonly noticed mild pain and dizziness were recorded.RESULTS: General findings: According the gender, 96 (90.5%) of them were women and 10 (9.5%) men. Median age was 47 ± 9 years. Cytological findings: 5 patients were with papillary carcinoma, 3 with Hurtle cell metaplasia, 1 follicu...
Assessing the Ultrasound Guided Fine Needle Aspiration in Diagnosis of Thyroid Nodules
Pakistan postgraduate medical institute, 2016
Objective: To decide the number of punctures in a biopsy procedure, Fine Needle Aspiration (FNA), needed for secured cytological evaluation of thyroid nodules. Materials and Methods: This cross-sectional analysis was carried out at Pakistan Institute of Medical Science, Islamabad (PMIS) during the period from January to December, 2016. A total of 94 patients participated in the population study according to the inclusion criteria. The diagnosis was the focal point of the research. Results: The participants in the study group aged around 51 years, while 86.2% among the patients were females. Since punctures were considered as an independent event, the first puncture produced decisive results in 77.5% of cases. The second and third puncture produced results in 82.1% and 73.2% of all cases relatively. With a view to increase the conclusive analysis at each puncture, two punctures have demonstrated indisputable results in 87.2% of cases, and three punctures, in 91.2% of cases with no less than one decisive result. Conclusion: Two punctures in fine-needle desire biopsies of thyroid nodules have prompt determination in 86.2% of cases in the evaluation recommending that there is no requirement for further punctures to securely acquire the analysis of thyroid nodules.
Ultrasound in Medicine & Biology, 2012
The objective of this study was to determine the rate of malignancy in thyroid nodules with an initial nondiagnostic fine needle aspiration. From October 2001 to April 2007, biopsies were performed on 1344 thyroid nodules in our practice. Biopsies were performed on nodules using 25-27 gauge needles, ultrasound guidance and multiple passes using both suction and capillary action. We retrospectively reviewed the results of these biopsies as well as any further management of nodules that received nondiagnostic results (IRB HUM00006459). Following initial biopsy, 295/1344 (21.9%) of nodules received nondiagnostic pathologic results. Of this population, 39 nodules (13.1%) were lost to follow-up. Of the remaining 256 nodules that received a repeat FNA, surgical excision, or greater than 24 months of clinical and imaging follow-up, only five cancers were detected, representing only 2% of the population that received an initial nondiagnostic biopsy result. All of these cancers were papillary neoplasms. When rigorous, ultrasound-guided, fine needle aspiration of thyroid nodules is performed, a nondiagnostic histopathologic result should not be interpreted as suspicious for thyroid cancer. Given the low rate of malignancy in this population (2%), we suggest that clinical and imaging follow-up of these nodules, opposed to repeat sampling, is warranted.
Value of fine-needle aspiration in evaluating large thyroid nodules
Head & Neck, 2016
Background. The American Thyroid Association (ATA) recommends using ultrasound-guided fine-needle aspiration (FNA) in order to evaluate supracentimetric and suspect thyroid nodules. The purpose of this study was to evaluate the effective use of FNA before surgery for nodules over 3 cm in diameter. Methods. In this retrospective study, we analyzed the results of ultrasound-guided FNA and postoperative histological analysis in 843 nodules >3 cm. Results. The FNA was informative in 42.6%. The correlation with the final histological analysis was 94.8% for benign nodules and 71.0% for malignant nodules. The FNA had a positive predictive value of 71%, a specificity of 97%, a sensitivity of 56%, and a 4.7% rate of falsenegative results. Conclusion. Because there is a nonnegligible FNA risk of error, notably allowing the evolution of a cancer in 1 of 20 cases, the FNA data should not delay surgical intervention for potentially suspect nodules >3 cm in diameter. V
ISRN Endocrinology, 2011
The objective was to analyze the results of UG-FNAB, performed in unselected consecutive patients with thyroid nodules. Methods. The UG-FNAB records were analyzed in this retrospective study. Indication for biopsy was the presence of at least one nodule detected by ultrasound. Results. 330 patients at mean age ± SD 48.4 ± 11.2 years; women/men = 12.8/1 were analyzed. From the total 596 nodules found 546 (91.6%) were investigated with 1231 punctures (2.3 per nodule and 3.7 per patient). Benign solitary nodules had 42.7%, multinodular goiter (MNG) 44.8%, inconclusive 4.8%, and others 2.1% and malignant nodules 5.5% of the patients (6.6% of solitary and 5.1% of MNG patients). The risk for a separate nodule in MNG to be malignant was 2.7%. Conclusions. UG-FNAB is a safe and reliable diagnostic approach for thyroid nodules. It is the method of choice for hypo- and isoechoic not purely cystic solitary nodules, regardless of the nodule size. In MNG, its positive predictive value and diagno...
Ultrasound-guided fine needle aspiration for thyroid nodules
2007
- Acadêmico de Medicina da Faculdade de Ciências Médicas da Fundação Lusíada, Santos. 2) Residente de Cirurgia Geral do Hospital Ana Costa, Santos. 3) Residente de Cirurgia de Cabeça e Pescoço do Hospital Ana Costa, Santos; Mestrando do Curso Pós-Graduação em Ciências da Saúde do Complexo Hospitalar Heliópolis, São Paulo. 4) Doutora em Oncologia pelo Curso de Pós-Graduação em Ciência da Fundação Antônio Prudente do Hospital do Câncer – A. C. Camargo, São Paulo. 5) Doutor em Medicina pelo Curso de Pós-Graduação em Otorrinolaringologia e Cirurgia de Cabeça e Pescoço da Universidade Federal de São Paulo – Escola Paulista de Medicina; Chefe da Divisão de Cirurgia e da Divisão de Ensino do Hospital Ana Costa, Santos; Docente do Curso Pós-Graduação em Ciências da Saúde do Complexo Hospitalar Heliópolis, São Paulo.
The objective of this study is to elucidate the use of ultrasonography guided fine-needle aspiration biopsies (UG-FNAB) in the evaluation of thyroid nodules. The study population consisted of 790 UG-FNAB in 719 patients whom were admitted to the our endocrinology clinic. The cytological results were classified as benign, follicular lesion or suspicious for malignancy, malignant and non-diagnostic. The results of 790 UG-FNAB of 719 patients were as follows: 567 (71.77%) benign, 97 (12.28%) non-diagnostic cytology, 43 (5.44%) atypia with undetermined significance, 81 (10.25%) follicular lesion or suspicious for malignancy, 2 (0.25%) malignant. In our study, thyroid carcinoma rate was found to be lower than current literature. Of the malignant nodules which were reported as papillary thyroid carcinoma by UG-FNAB cytology, both were female, euthyroid and have single nodule in their thyroid gland. One of the patient (39 years old) had a micro nodule (< 1 cm in diameter) that it had an isoechoic pattern with regular margin on thyroid ultrasonography; whereas the other one (79 years old) had macro nodule (>1 cm diameter) that it had, hypoechoic pattern with irregular margin. None of them have calcifications in their nodules. Multidisciplinary approach including endocrinologists, radiologists and pathologists is essential for the management of patients with thyroid nodules to avoid missestimation of the risk of thyroid cancer.
Evaluation of a dedicated ultrasound fine needle aspiration service for thyroid nodules
Sonography, 2018
Introduction: We studied whether: (1) a quality-focused thyroid fine needle aspiration (FNA) service reduced the non-diagnostic (ND) rate of FNA; (2) the implementation of thyroid FNA selection criteria resulted in higher proportion of Bethesda V and VI cytology and malignant histopathology; and (3) impact of radiologist's level of experience on ND rates. Method: The imaging and pathology computer databases were retrospectively searched for all patients who had thyroid FNAs at our hospitals from July 2004 to December 2016. Results: Three hundred thirty-eight and 609 patients in pre-thyroid and post-thyroid service groups, respectively, were evaluated. The ND rate of 36.7% in pre-thyroid service was significantly higher than post-thyroid service at 14.6% (p < 0.0001). The rates of Bethesda V and VI cytology in the pre-thyroid service group did not differ significantly from the post-thyroid group (p = 0.266; p = 0.069). There was no significant difference in the histopathologic malignancy rates between the two groups (p = 0.531). There was no significant difference in the ND rates of radiologists with varying experience (p = 0.873). Discussion: On-site cytology improved the ND rate of ultrasound-guided thyroid FNA. Implementation of FNA selection criteria did not alter the rates of Bethesda V and VI cytology and malignant histopathology. The experience of radiologists did not significantly influence ND rates.
Molecular and Clinical Oncology, 2015
The aim of the present study was to verify the optimal method to obtain enough fine-needle aspiration (FNA) materials for detecting thyroid malignancy. A prospective study was performed by comparing two different regional standards of care. In one group a traditional FNA method mainly used in Asian countries, including China, was performed in which a single pass of a 22-G needle was applied with or without aspiration. In the other group, the method mainly used in Western countries was performed in which three passes of a 25-G needle with non-aspiration were undertaken for thyroid nodules. The study included 718 thyroid nodules from 695 patients. These nodules were allocated for three different methods of performing thyroid FNA. There were 332 thyroid nodules subjected to the traditional Asian FNA method using a 22-G needle with aspiration for 142 nodules and non-aspiration for 190 nodules. FNA using the Western method was performed with three passes of non-aspiration using 25 G for 386 nodules. All the FNAs were performed with the guidance of ultrasound. The components of the nodules were documented. All the samples were reported using the Bethesda System for Reporting Thyroid Cytopathology. Among the 22 G group, the non-diagnostic rate in the aspiration group was as high as 76.76%, which was significantly higher than 44.21% in the non-aspiration group (P<0.01).