Delayed presentation, diagnosis, and psychosocial aspects of male breast cancer (original) (raw)
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Male cancer: a qualitative study of male breast cancer
Breast, 2000
S U M M A R Y. Breast cancer is a rare condition in males. There is a dearth of information about the psychological and social impact of this condition. Data from six in-depth interviews with men who had breast cancer identified seven major issues. These were associated with delay in diagnosis, shock, stigma, body image, causal factors, the provision of information and emotional support. The findings from this small study suggest that there are psychological and social factors for men diagnosed with breast cancer which have implications for their care and management. The recommendations arising from this study are the development of a structured education programme aimed at all primary health-care professionals; with availability of pre and postoperative gender-specific information to alleviate the potential psychological problems associated with the diagnosis; and provision of appropriate support/counselling services for partners of patients. #
MALE BREAST CANCER: SIGNS, SYMPTOMS, AND TREATMENT: A REVIEW
International Journal of Creative Research Thoughts , 2020
Male breast cancer (MBC) is an infrequent and uncommon condition. It accounts 1% than other cancer diagnosed in men. The rationale for low incidence among men is due to difference in hormonal environment and relatively poor breast tissue count in men. The disease is also diagnosed at later stages because of lack of awareness. In Asia most of the males hide about this disease due to social psychology. There is limited literature and published data on MBC due to low incidence of disease. This review deals with etiology, pathology, risk factors, treatment and psychological trauma in MBC patients. While in both genders breast carcinomas share similar features, significant variations exist. Most studies are very limited on the men with breast cancer. Therefore, most evidence on male breast cancer is extracted from female research. However, we will learn more about them when a lot of these little studies on male breast cancer are put together. This review stresses on the occurrence, etiology, clinical characteristics, diagnosis, treatment, pathology, survival and MBC-related prognostic factors.
Male breast cancer: a 5-year experience from a State Cancer Institute
2021
Background: Male breast cancer (MBC) is an uncommon malignancy accounting for <1% of all cancers in men and <1 % of overall breast cancer cases. Although there are many similarities between MBC and female breast cancer (FBC), they are not identical in clinical behaviour. There is need to understand the exact biological behavior of MBC.Methods: A retrospective observational study was done at State Cancer Institute, IGIMS, Patna which included all MBC patients registered during a 5-year study period (January 2016 to April 2021). 16 consecutive cases of MBC were identified and their detailed clinicopathological profile was analyzed.Results: MBC accounted for 1.10% of the total breast cancer cases. The median age of presentation was 58 years. Most common presentation was lump. Invasive ductal carcinoma (IDC) was most common histology. Majority of the patient presented to us in advanced stage. Estrogen receptor (ER)/progesterone receptor (PR) status was found to be positive in 12 p...
Male breast cancer: thirteen years experience of a single center
International seminars in surgical oncology : ISSO, 2009
This retrospective study analysed the epidemiological, clinical, and therapeutic profiles of breast cancer in males. We report our experience at the Hospital of the University of Baskent, where 20 cases of male breast cancer were observed and treated between 1995-2008. Median age at presentation was 66,7 +/- 10,9 years. Average follow-up was 63 +/- 18,5 months. The main presenting symptom was a mass in 65% of cases (13 patients). Ynvasive ductal carcinoma was the most frequent pathologic type (70% of cases). Male breast cancer patients have an incidence of prostate cancer higher than would be predicted in the general population. Cause of men have a higher rate of ER positivity the responses with hormonal agents are good.
Clinical management of breast cancer in males: a report of four cases
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2002
Breast cancer in men is a rare cancer manifestation, accounting for less then 1% of all breast cancers in both genders. The incidence in Germany during the last years has been approximately 1.0 per year/100,000. In the US, only 0.2% of all malignancies in men. Predisposing risk factors seem to include radiation exposure, hereditary factors, estrogen administration, and diseases associated with hyperestrogenism, such as cirrhosis of the liver or genetic syndromes (i.e. Klinefelter disease). The incidence of male breast cancer is increased in families with a number of ®rst degree relatives affected with breast or prostate cancer. An increased risk of male breast cancer has been reported in families with a mutation of the breast cancer susceptibility gene BRCA-2. For a period of decades, prognosis of breast cancer in males was thought to be worse than that of female patients. Data and cases being published demonstrate that prognosis and strategies of treatment in male breast cancer do not differ from those in females. The cases presented clearly demonstrate that diagnostic work-up, staging procedures and treatment options for primary treatment and advanced stages are identical compared to the recommendation for female breast cancer.
A retrospective study of treatment and outcome in 39 cases of male breast cancer
Hematology/Oncology and Stem Cell Therapy, 2008
M ale breast cancer (MBC) is a rare disease that accounts for less than 1% of all cancers in men and less than 1% of all diagnosed breast cancers. 1 MBC and female breast cancer differ in age at diagnosis, frequency of the histological types, and frequency of expression of hormone receptors. The median age at diagnosis in men is 68 years compared with 63 years in women. 2t4 Men with breast cancer have a higher occurrence of ductal histology. More than 85% of all cases are invasive ductal carcinomas; in women the frequency of ductal histology is 70% to 75%. 5 Estrogen, androgen, and progesterone steroid receptor expression is also higher in MBC. 5,6 Despite the biological differt t ences, the clinical outcome for breast cancer in men is similar to that in women when they are matched for age, treatment, and stage of cancer. 5,7 Optimal managet t ment of MBC is not clearly established and treatment guidelines are scarce. The literature on male breast cant t cer consists mainly of casetcontrol and retrospective A retrospective study of treatment and outcome in 39 cases of male breast cancer
The Management and Outcomes of Male Breast Cancer
Journal of Breast Health, 2016
Objective: Due to a lack of sufficient data, the treatment protocols for male breast cancer are usually the same as those used for female breast cancer. The aim of the current study was to present our clinical experience with male breast cancer. Materials and Methods: The records of 37 patients who were treated for male breast cancer in our hospital between 2004 and 2014 were reviewed retrospectively. The data of patients were recorded and analyzed. Results: The mean age of the patients was 63.03±12.36 years. Thirty-three patients (89.2%) had invasive ductal carcinoma, two (5.4%) had ductal carcinoma in situ, and two had invasive lobular carcinoma (5.4%). The most common molecular subtype was luminal A (17 cases, 45.9%). Twentynine patients with male breast cancer underwent mastectomy and two underwent breast conserving surgery. Axillary lymph node dissection was performed in 25 patients. The most common surgical procedure was modified radical mastectomy. Distant metastases were present in 17 (45.9%) patients. Overall, the 5-year survival was 60%. The 5-year survival was 100% for those with stage 0-I disease, 87% for stage II, and 42% for stage III. The 3-year survival was 14% for stage IV. Conclusion: Patients with male breast cancer presented at an older age, a later stage, and with earlier metastasis. Early metastasis and death increases with increasing stage. Poor prognosis correlates with late admission. Data from different centers should be compiled and reviewed in order to determine a specific treatment protocol for male breast cancer; each paper published reveals new data.
International Journal of Clinical Medicine, 2014
Objective: To review presentation, diagnosis, treatment and prognosis of male breast cancer. Method: A systematic review of the English language literature between 1990 and 2013 was conducted to identify studies relevant to the objective. Searches were carried out on the database PubMed, by using the title term "male breast cancer". Results: The majority of male patients present with a painless, firm, subareolar lump. Experience of male breast imaging is good but limited. However, there is no definitive therapeutic algorithm. Men are often treated with mastectomy instead of breast conserving surgery and mostly tamoxifen is used as an adjuvant therapy. The most important prognostic factors are tumor size and lymph node status in the armpit. Conclusion: More increased awareness and further research are needed to improve the diagnosis and treatment of this disease.
Male breast cancer: a review of the literature
European Journal of Cancer, 1998
Although breast cancer is uncommon in men, it can cause signi®cant morbidity and mortality. The current review was undertaken to determine whether strategies applied for the evaluation and treatment of breast cancer in females are appropriate in male breast cancer. Male breast cancer has biological diVerences compared with female breast cancer, including a high prevalence in certain parts of Africa, a higher incidence of oestrogen receptor positivity and more aggressive clinical behaviour. It responds to hormonal manipulation and chemotherapy, but optimal treatment regimens in males are unknown. Male breast cancer remains an uncommon disease. Most of our current knowledge regarding its biology, natural history and treatment strategies has been extrapolated from its female counterpart. Much research is needed to further characterise the molecular biological properties of male breast tumours and their prognostic signi®cance, and to devise treatment strategies, including optimal chemotherapy regimens. #
An Update on the General Features of Breast Cancer in Male Patients- a Literature Review
Male breast cancers are uncommon, as men account for less than 1 percent of all breast carcinomas. Among the predisposing risk factors for male breast cancer, the following appear to be significant: a) breast/chest radiation exposure, b) estrogen use, diseases associated with hyper-estrogenism, such as cirrhosis or Klinefelter syndrome, and c) family health history. Furthermore, there are clear familial tendencies, with a higher incidence among men who have a large number of female relatives with breast cancer and d) major inheritance susceptibility. Moreover, in families with BRCA mutations, there is an increased risk of male breast cancer, although the risk appears to be greater with inherited BRCA2 mutations than with inherited BRCA1 mutations. Due to diagnostic delays, male breast cancer is more likely to present at an advanced stage. A core biopsy or a fine needle aspiration must be performed to confirm suspicious findings. Infiltrating ductal cancer is the most prevalent form ...