Differential antiviral activities of respiratory syncytial virus (RSV) inhibitors in human airway epithelium (original) (raw)

Differential antiviral activities of RSV inhibitors in human airway epithelium

Mieke Boon

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Respiratory Syncytial Virus Can Infect Basal Cells and Alter Human Airway Epithelial Differentiation

Henry Danahay, Rachel Fearns

PLoS ONE, 2014

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Disruption of the Airway Epithelial Barrier in a Murine Model of Respiratory Syncytial Virus Infection

Terri Harford

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2018

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In vitro modeling of respiratory syncytial virus infection of pediatric bronchial epithelium, the primary target of infection in vivo

Mike Shields

Proceedings of the National Academy of Sciences, 2012

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Oral Efficacy of a Respiratory Syncytial Virus Inhibitor in Rodent Models of Infection

Ivette Medina

Antimicrobial Agents and Chemotherapy, 2004

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Growth of Respiratory Syncytial Virus in Primary Epithelial Cells from the Human Respiratory Tract

Ricardo Gonzales

Journal of Virology, 2005

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Induction and antagonism of antiviral responses in respiratory syncytial virus-infected pediatric airway epithelium

Mike Shields

Journal of Virology, 2015

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Respiratory Syncytial Virus Persistence in the Lungs Correlates with Airway Hyperreactivity in the Mouse Model

Asunción Mejías

The Journal of Infectious Diseases, 2008

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Discovery of an Oral Respiratory Syncytial Virus (RSV) Fusion Inhibitor (GS-5806) and Clinical Proof of Concept in a Human RSV Challenge Study

Robert Strickley, Tomas Cihlar

Journal of medicinal chemistry, 2015

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GS-5806 Inhibits a Broad Range of Respiratory Syncytial Virus Clinical Isolates by Blocking the Virus-Cell Fusion Process

Dorothy Theodore

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Comparative Effects of Two Neutralizing Anti-Respiratory Syncytial Virus (RSV) Monoclonal Antibodies in the RSV Murine Model: Time versus Potency

Perla Chavez

Antimicrobial Agents and Chemotherapy, 2005

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Orally Active Fusion Inhibitor of Respiratory Syncytial Virus

Nicholas Meanwell

Antimicrobial Agents and Chemotherapy, 2004

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Respiratory Syncytial Virus: Infection, Detection, and New Options for Prevention and Treatment

Steven Drews

Clinical Microbiology Reviews, 2016

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The Pharmacokinetics, Antigenicity, and Fusion-Inhibition Activity of RSHZ19, a Humanized Monoclonal Antibody to Respiratory Syncytial Virus, in Healthy Volunteers

Diane JOrkasky

Journal of Infectious Diseases, 1996

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Respiratory Syncytial Virus Inhibits Ciliagenesis in Differentiated Normal Human Bronchial Epithelial Cells: Effectiveness of N-Acetylcysteine

isidoro martinez

PLoS ONE, 2012

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Evaluation of Small Molecule Combinations against Respiratory Syncytial Virus In Vitro

Ralf Altmeyer

Molecules, 2021

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Anti-Respiratory Syncytial Virus (RSV) Neutralizing Antibody Decreases Lung Inflammation, Airway Obstruction, and Airway Hyperresponsiveness in a Murine RSV Model

ANA GOMEZ

Antimicrobial Agents and Chemotherapy, 2004

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Isolation of a Second Recombinant Human Respiratory Syncytial Virus Monoclonal Antibody Fragment (Fab RSVF2–5) that Exhibits Therapeutic Efficacy In Vivo

James Crowe

The Journal of Infectious Diseases, 1998

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Challenges and opportunities in developing respiratory syncytial virus therapeutics

James Crowe

The Journal of infectious diseases, 2015

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Pharmacologic Advances in the Treatment and Prevention of Respiratory Syncytial Virus

Louis Saravolatz

Clinical Infectious Diseases, 2010

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Morphogenesis of respiratory syncytial virus in human primary nasal ciliated epithelial cells occurs at surface membrane microdomains that are distinct from cilia

Puisan Wong, Raihan Jumat

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Respiratory Syncytial Virus Infection in Human Bone Marrow Stromal Cells

Sulachni Chandwani

American Journal of Respiratory Cell and Molecular Biology, 2011

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