Determination of Turkish Norms of Psychometric Tests For Diagnosing Minimal Hepatic Encephalopathy and Proposal of a Simplified Paper Pencil Test Battery (original) (raw)
Background: Psychometric hepatic encephalopathy score (PHES) needs standardization for countries and is used for minimal hepatic encephalopathy (mHE) diagnosis. Assessing it is cumbersome.Aims: To standardize PHES for Turkish patients and compare it with German norms; to determine mHE prevalence with two different methods and to assess whether the PHES test can be simplified.Methods: Healthy volunteers (n=816; 400 male) and cirrhotics (n=124; 58 male) were included. PHES score threshold was set at ≤-5 points and that of critical flicker frequency (CFF) at <39 Hz for mHE diagnosis. For comparing German and Turkish norms, datasets were combined. Multiple backward procedure was applied. Receiver operating characteristic (ROC) curves were created for assessing diagnostic capabilities of single subtests of the PHES test. Results: Turkish norms displayed non-linear dependence on age and education. Rate of mHE in compensated cirrhotics was 29.8% and 27.4% with PHES and CFF tests, respec...
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