Classification of odontogenic cysts and tumors - Antecedents (original) (raw)

Odontogenic cysts and tumors

Objective: The aim of the study was to determine the relative incidence of odontogenic cysts and tumors in Karachi-Pakistan. Study design: This was a retrospective observational study of 100 cysts and 141 tumors that were included in the database of 6000 patients of histopathological diagnoses of Dow Diagnostic Reference and Research laboratory and The Laboratory, from 2001-2010. Following variables were recorded:gender, age and clinical characteristics of the lesions (size and location).A descriptive analysis was done using SPSS version 16. Results: The incidence of the odontogenic cyst was 1.6% and 2.35% for the tumors. The cysts (61%) and tumors (63.1) were both more prevalent in males.Most frequent diagnosis was radicular cysts (53%) and odontogenic keratocystic tumor (27%). The most common location for cyst (51%) and tumors (68%) both was mandible. Conclusion: Knowledge of the biological and histological behavior of odontogenic cysts and their frequency are key aspects for ensuring early detection and adequate treatment.

Prevalence of Odontogenic Cysts and Tumors – A Clinicopathological Study

Medico-Legal Update, 2020

Background: The incidence and frequency of odontogenic cysts and tumors depends on the different geographic location. Odontogenic cysts and tumors are lesions that arise from the tooth apparatus or its remnants. The purpose of this study was to determine the prevalence of odontogenic cysts and tumors over a period of 5 years 9 months and to compare our results with other published studies.

Analyses of odontogenic tumours: the most recent classification proposed by the World Health Organization (2017)

Medicina Oral Patología Oral y Cirugia Bucal, 2020

Background: The fourth edition of the ''WHO Classification of Head and Neck Tumours'' was published in January 2017 and includes a classification of odontogenic tumours. This review aims to examine the changes made in this new classification in comparison with the previous classification of 2005. Material and Methods: An electronic search was conducted in the PubMed, Scopus and Cochrane databases with the keywords "odontogenic tumor", "WHO classification" and "update". Studies published from January 2009 to April 2019 with a high level of scientific evidence were included, but studies not published in English, epidemiological studies and studies with a low level of evidence were excluded. Results: The initial search found 457 articles and after eliminating duplicates, 8 studies were selected for full-text assessment. After excluding 3 epidemiological studies, 5 articles were finally included. These studies were stratified by their level of scientific evidence using SORT criteria (Strength of Recommendation Taxonomy). Conclusions: The new odontogenic tumour list has been simplified with the objective of improving its role as an international guide for diagnosis. Some changes have been possible thanks to the application of immunohistochemistry and molecular genetic techniques that allow better characterization of certain tumours. Further clinicopathological and molecular studies are needed so that this new classification can be consolidated and/or amended.

Controversies in Odontogenic Tumours: Review

Sultan Qaboos University medical journal, 2017

Odontogenic tumours are lesions that occur solely within the oral cavity and are so named because of their origin from the odontogenic (i.e. tooth-forming) apparatus. Odontogenic tumours comprise a variety of lesions ranging from non-neoplastic tissue proliferations to benign or malignant neoplasms. However, controversies exist regarding the pathogenesis, categorisation and clinical and histological variations of these tumours. The recent 2017 World Health Organization classification of odontogenic tumours included new entities such as primordial odontogenic tumours, sclerosing odontogenic carcinomas and odontogenic carcinosarcomas, while eliminating several previously included entities like keratocystic odontogenic tumours and calcifying cystic odonogenic tumours. The aim of the present review article was to discuss controversies and recent concepts regarding odontogenic tumours so as to increase understanding of these lesions.

Neoplastic potential of odontogenic cysts

Contemporary Clinical Dentistry, 2011

Odontogenic cysts and tumors are distinct entities and quite a common occurrence in the jaw bones. The lining of odontogenic cysts shows a potential for neoplastic transformation to non odontogenic malignancies like squamous cell carcinoma and mucoepidermoid carcinoma, and odontogenic tumors like ameloblastoma and adenoamatoid odontogenic tumor (AOT). AOT is a benign, epithelial odontogenic tumor, common site being the anterior maxilla. Its origin from a dentigerous cyst and in the mandible is rare. A case of an AOT arising from a dentigerous cyst associated with an impacted permanent mandibular left lateral incisor is reported.

Odontogenic tumors: An 11‐year international multicenter study

Oral Diseases, 2020

Cases of OTs were selected and classified according to the current WHO classification (2017) (Wright and Vered, 2017). The hematoxylin and eosin-stained sections were re-evaluated. Data regarding histopathological type, gender, age and anatomical site, were obtained from patient records. The cases of OTs were divided according to the oral pathology center and its corresponding geographical areas. Based on the 10-year analysis, Brazil 1 was the center with the highest number of cases of OTs (437 cases), followed by Israel (163 cases), Finland (115 cases), and Brazil 2 (108 cases).

Odontogenic tumors: A collaborative study of 218 cases diagnosed over 12 years and comprehensive review of the literature

Medicina oral, patología oral y cirugía bucal, 2015

The objective of this study was to analyze the frequency and distribution of odontogenic tumors (OTs) in the Cappadocia region of Turkey, and to compare the findings with those reported in the literature. The records of the Oral and Maxillofacial Surgery and Pathology Departments at Erciyes University, with histologic diagnosis of odontogenic tumors (based on the World Health Organization classification, 2005), over a 12-year period, were analyzed. The relative frequency of different types of tumors was also analyzed and compared with the literature. OTs in the present study constituted 2.74% of all the 7,942 registered biopsies. A total of 218 cases of OTs were collected and reviewed. Of these, (94.04%) were benign and (5.96%) were malignant. The mandible was the most commonly affected anatomic location, with 170 cases (77.9%). Ameloblastoma with a predilection for the posterior mandible was the most frequent odontogenic tumor (30.28%), followed by keratocystic odontogenic tumor (1...