original ) (raw )Crystal structures of free and antagonist-bound states of human α9 nicotinic receptor extracellular domain
Petros Giastas , Dafni Chroni-tzartou
Nature Structural & Molecular Biology, 2014
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Molecular modeling of the α9α10 nicotinic acetylcholine receptor subtype
Edwin Perez
Bioorganic & Medicinal Chemistry Letters, 2009
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Recent advances in understanding the structure of nicotinic acetylcholine receptors
Konstantinos Poulas
Iubmb Life, 2009
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Emerging structure of the Nicotinic Acetylcholine receptors
Arthur KARLIN
Nature Reviews Neuroscience, 2002
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Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an α-conotoxin PnIA variant
Maxim Zhmak
Nature Structural & Molecular Biology, 2005
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Molecular modeling of the alpha9alpha10 nicotinic acetylcholine receptor subtype
Edwin Perez
Bioorganic & medicinal chemistry letters, 2009
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Molecular basis of the two nonequivalent ligand binding sites of the muscle nicotinic acetylcholine receptor
P. Blount
Neuron, 1989
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Topology of ligand binding sites on the nicotinic acetylcholine receptor
HUGO JESUS URBINA ARIAS
Brain Research Reviews, 1997
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Molecular dissection of subunit interfaces in the nicotinic acetylcholine receptor
Nina Bren
Journal of Physiology-paris, 1998
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A computational investigation on the role of glycosylation in the binding of alpha1 nicotinic acetylcholine receptor with two alpha-neurotoxins
Konstantinos Poulas
2011
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Agonist-Induced Conformational Changes in the Extracellular Domain of 7 Nicotinic Acetylcholine Receptors
Bob Rosenberg
Molecular Pharmacology, 2003
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Nicotine and Carbamylcholine Binding to Nicotinic Acetylcholine Receptors as Studied in AChBP Crystal Structures
Titia Sixma
Neuron, 2004
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A gating mechanism proposed from a simulation of a human 7 nicotinic acetylcholine receptor
Richard Henchman
Proceedings of the National Academy of Sciences, 2005
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Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor
Ken Veys
Proceedings of the National Academy of Sciences, 2015
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Hydrophobic residues at position 10 of α-conotoxin PnIA influence subtype selectivity between α7 and α3β2 neuronal nicotinic acetylcholine receptors
David J Adams
Biochemical pharmacology, 2014
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An hypothesis concerning the molecular structure of the nicotinic acetylcholine receptor
john smythies
Medical Hypotheses, 1980
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Initial Coupling of Binding to Gating Mediated by Conserved Residues in the Muscle Nicotinic Receptor
Steven m. M Sine
The Journal of General Physiology, 2005
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Structure-Activity Relationships in a Peptidic α7 Nicotinic Acetylcholine Receptor Antagonist
Peter Luginbuhl
Journal of Molecular Biology, 2000
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Molecular simulation study of the unbinding of α-conotoxin [ϒ4E]GID at the α7 and α4β2 neuronal nicotinic acetylcholine receptors
Abishek Kalpathi Suresh
Journal of molecular graphics & modelling, 2016
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Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist α-conotoxin OmIA that discriminates α3 vs. α6 nAChR subtypes
Baldomero Olivera
Biochemical and Biophysical Research Communications, 2006
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The Nicotinic Acetylcholine Receptor, A Model of Ligand-Gated Ion Channels
Jean-luc Galzi
The Jerusalem Symposia on Quantum Chemistry and Biochemistry, 1992
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Molecular Interactions between Ligands and Nicotinic Acetylcholine Receptors Revealed by Studies with Acetylcholine Binding Proteins
Hugo Arias
Journal of Thermodynamics & Catalysis, 2012
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A structural model for the ligand-binding sites at the nicotinic acetylcholine receptor
Wolfram Saenger
FEBS Letters, 1984
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Identification of a Negative Allosteric Site on Human α4β2 and α3β4 Neuronal Nicotinic Acetylcholine Receptors
Collin Stultz
PLoS ONE, 2011
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Ligand Selectivity for the Acetylcholine Binding Site of the Rat α4β2 and α3β4 Nicotinic Subtypes Investigated by Molecular Docking
Linjing Mu , William H Bisson
Journal of Medicinal Chemistry, 2005
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An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors
Stuart Edelstein
The EMBO Journal, 2003
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Structural principles of distinct assemblies of the human α4β2 nicotinic receptor
Richard Walsh
Nature, 2018
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Non-equivalent Ligand Selectivity of Agonist Sites in (α4β2) 2 α4 Nicotinic Acetylcholine Receptors
patricio vasquez
Journal of Biological Chemistry, 2014
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A computational model of the nicotinic acetylcholine binding site
Isabel Iriepa Canalda
Journal of Computer-aided Molecular Design, 1999
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Modeling Binding Modes of α7 Nicotinic Acetylcholine Receptor with Ligands: The Roles of Gln117 and Other Residues of the Receptor in Agonist Binding
Clare Stokes
Journal of Medicinal Chemistry, 2009
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