Endophthalmitis Caused by Achromobacter Xylosoxidans After Cataract Surgery (original) (raw)

Clinical, Microbiological Profile and Treatment Outcome of Ocular Infections Caused by Achromobacter xylosoxidans

Cornea, 2009

Purpose: To study the microbiological profile and outcome of ocular infections caused by Achromobacter xylosoxidans. Methods: Medical and microbiology records of patients with A. xylosoxidans ocular infections managed between May 2007 and December 2007 were reviewed. Results: The authors identified 10 patients whose eyes were infected by A. xylosoxidans during the study period. Of 10 patients, 8 had microbial keratitis, of whom 6 developed an infection after penetrating keratoplasty. The remaining 2 patients had endophthalmitis. The Gram-stained smear did not reveal any organism in 6 of 10 cases. In the 4 remaining cases, Gram-negative bacilli were reported. Out of 10 isolates, 9 were sensitive to ceftazidime, 7 to amikacin, 5 to ciprofloxacin, and 3 to ofloxacin, gatifloxacin, and chloramphenicol. Only one isolate was sensitive to moxifloxacin. Of the 6 patients with graft infection, 2 patients were lost to follow-up, infection was resolved in 3 patients, and the infection remained active in 1 patient. The two patients with endophthalmitis responded to antibacterial therapy and showed improved visual acuity. Infection was resolved in 2 patients with keratitis. Conclusion: Although A. xylosoxidans ocular infections are rare, one should retain a high index of clinical suspicion in patients who present with slowly progressive disease characterized by a localized infiltration and show Gram-negative bacilli on smear examination.

Keratitis Due to Achromobacter xylosoxidans in a Contact Lens User

Eye & Contact Lens-science and Clinical Practice, 2018

Objectives: Ocular infections due to Achromobacter xylosoxidans are extremely uncommon; their diagnosis is a challenge and the optimal treatment remains controversial. We present a case of A. xylosoxidans in a contact lens user and a review of the literature to facilitate diagnostic suspicion and empirical therapeutic management. Methods: Review of the literature in PubMed and MEDLINE. We also document a case diagnosed in our department in January 2016.