Clinical epidemiological study of Hepatitis B and C (original) (raw)

Ali et al. / Current Science Perspectives 1(2) (2015) 91-95 92 HCV patients from the different part of the world can be divided into six main genotypes. The major clinical difference between genotypes is the response to antiviral therapy (Simmonds et al., 1999). The transmission of HCV is declining worldwide as a result of the screening of blood products and implementation of standard precautions (Armstrong et al., 2000). Normalization of liver enzyme levels, viral suppression and clearance, reduction in histologic scores of liver inflammation or fibrosis, and combinations of these outcomes have been used to measure response to antiviral drugs or development of antiviral resistance (Lok and McMahon, 2007; Hoofnagle et al., 2007). Progression from acute to chronic HBV infection is influenced by the patient's age at acquisition of the virus; age is also related to the clinical expression of HBV infection between high-prevalence (e.g., Asian) and lowprevalence (e.g., Western) count...