Isolated Rheumatic Mitral Regurgitation with Giant Left Atrium in Sinus Rhythm – A Case Report (original) (raw)

Isolated mitral regurgitation is a relatively uncommon presentation of chronic rheumatic heart disease 1. Chronic nature of rheumatic mitral regurgitation causes gradual dilatation of the left atrium with little increase in pressure and therefore relatively fewer symptoms. However, occasionally the dilatation of LA is so severe, it is termed giant LA. Giant left atrium is a rare condition, with a reported incidence of 0.3%, and occurs following mainly rheumatic mitral valve disease 2. Atrial fibrillation is almost always present 3 predisposing to thromboembolic complications. A subset of patients may develop severe dysphagia from esophageal compression or hoarseness from laryngeal nerve impingement 4. Here we are presenting a case of isolated mitral regurgitation with giant left atrium in sinus rhythm. Case Report|: A 30-year-old woman normotensive, non-diabetic presented with the complain of SOB and palpitation for 2 ½ months and leg swelling for 10 days. 2 ½ months back, after 10 days of delivery of her 3 rd child, she developed SOB which was initially present on exertion (NYHA-II) and relieved by rest, but since last 10 days, it was present on minimal exertion or rest (NYHA III-IV) with orthopnea but no PND. She also had dry cough but no hemoptysis or diurnal and seasonal variation. She also had palpitation which occurred with SOB during exertion and was relieved by rest. It was regular and not associated with dizziness or syncope. Since last 10 days, she also developed swelling of legs which was gradually increasing, associated with decreased urine output but no puffiness of face or abdominal swelling. She didn't have history of chest pain,

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Doppler echocardiography distinguishes between physiologic and pathologic “silent” mitral regurgitation in patients with rheumatic fever

Clinical Cardiology, 1997

Background: The diagnosis of rheumatic fever is based on physical findings (major) and supporting laboratory evidence (minor) as defined by the Jones criteria. Rheumatic carditis is characterized by auscultation of a mitral regurgitant murmur. Doppler echocardiography, however, may detect mitral regurgitation when there is no murmur ("silent" mitral regurgitation), even in normal individuals. Hypothesis: The hypothesis of this study was that physiologic mitral regurgitation can be differentiated from pathologic "silent" mitral regurgitation by Doppler echocardiography. Methods: The study group consisted of 68 patients (2-27 years) with normal two-dimensional imaging and Doppler evidence of mitral regurgitation but no murmur. Patients with rheumatic fever (n = 37) met Jones criteria (chorea in 20, arthritis in 17). Patients without rheumatic fever (n = 3 1) were referred for innocent murmur (n = 7), abnormal electrocardiogram (n = 13), and chest pain (n = 11). Echoes were independently reviewed by two cardiologists blinded to the diagnosis. Pathologic mitral regurgitation was defined as meeting the following four criteria: (1) length of colorjet > 1 cm, (2) color jet identified in at least two planes, (3) mosaic colorjet, and (4) persistence of the jet throughout systole. Jet orientation was also noted. Results: Using the above criteria, there was agreement in echo interpretation of pathologic versus physiologic mitral regurgitation in 67 of 68 patients (interobserver variability of 1.5%).

Unusual Giant Right Atrium in Rheumatic Mitral Stenosis and Tricuspid Insufficiency

Case Reports in Cardiology, 2011

Dilation and hypertrophy of the atria occur in patients with valvular heart disease especially in mitral regurgitation, mitral stenosis or tricuspid abnormalities. In sub-saharan Africa, rheumatic fever is still the leading cause of valvular heart disease. We report a case of an unusual giant right atrium in context of rheumatic stenosis and severe tricuspid regurgitation in a 58-year-old woman.

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