Importance of glucocorticoid receptors in the physiopathology of Alzheimer's disease (original) (raw)
Subchronic Glucocorticoid Receptor Inhibition Rescues Early Episodic Memory and Synaptic Plasticity Deficits in a Mouse Model of Alzheimer's Disease
Scherazad Kootar
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015
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Enduring glucocorticoid-evoked exacerbation of synaptic plasticity disruption in male rats modelling early Alzheimer’s disease amyloidosis
Neng-wei Hu
Neuropsychopharmacology
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Glucocorticoids Increase Amyloid-beta and Tau Pathology in a Mouse Model of Alzheimer's Disease
Benno Roozendaal
Journal of Neuroscience, 2006
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Decreased levels of nuclear glucocorticoid receptor protein in the hippocampus of aged Long-Evans rats with cognitive impairment
Jung-Soo Han
Brain Research, 2012
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Glucocorticoid receptor protein expression in human hippocampus; stability with age
Mitsuhiro Kawata
Neurobiology of Aging, 2013
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The role of glucocorticoids in brain aging and Alzheimer's disease: An integrative physiological hypothesis
Philip Landfield
Experimental Gerontology, 1994
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Targeting glucocorticoid receptors prevents the effects of early life stress on amyloid pathology and cognitive performance in APP/PS1 mice
Paul Lucassen
Translational psychiatry, 2018
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A New Glucocorticoid Hypothesis of Brain Aging: Implications for Alzheimers Disease
Philip Landfield
Current Alzheimer Research, 2007
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Rosiglitazone reverses memory decline and hippocampal glucocorticoid receptor down-regulation in an Alzheimer’s disease mouse model
Luis Escribano, Alberto Pérez-mediavilla
Biochemical and Biophysical Research Communications, 2009
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Selective reduction of glucocorticoid receptor immunoreactivity in the hippocampal formation and central amygdaloid nucleus of the aged rat
L. Agnati
Brain Research, 1991
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Glucocorticoid receptors modulate dendritic spine plasticity and microglia activity in an animal model of Alzheimer's disease
Mario Buffelli
Neurobiology of Disease, 2019
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Loss of glucocorticoid receptor phosphorylation contributes to cognitive and neurocentric damages of the amyloid-β pathway
Stephen D Ginsberg
Acta neuropathologica communications, 2022
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Overexpressing the Glucocorticoid Receptor in Forebrain Causes an Aging-Like Neuroendocrine Phenotype and Mild Cognitive Dysfunction
Stan Watson
Journal of Neuroscience, 2007
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Plasticity of hippocampal corticosteroid receptors during aging in the rat
osborne ALMEIDA
The FASEB Journal
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Greater glucocorticoid receptor activation in hippocampus of aged rats sensitizes microglia
Ruth Barrientos
Neurobiology of Aging, 2014
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Corticosterone and related receptor expression are associated with increased β-amyloid plaques in isolated Tg2576 mice
Carla Yuede
Neuroscience, 2008
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Insights into the Therapeutic Potential of Glucocorticoid Receptor Modulators for Neurodegenerative Diseases
Rachida Guennoun
International Journal of Molecular Sciences, 2020
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The selective glucocorticoid receptor modulator CORT108297 restores faulty hippocampal parameters in Wobbler and corticosterone-treated mice
Maria Meyer
The Journal of Steroid Biochemistry and Molecular Biology, 2014
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Increased affinity of type II corticosteroid binding in aged rat hippocampus
Philip Landfield, J. Charles Eldridge
Experimental Neurology, 1989
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The Glucocorticoid Hypothesis of Age-Related Hippocampal Neurodegeneration: Role of Dysregulated Intraneuronal Calcium
P. Landfield, J. Charles Eldridge
Annals of the New York Academy of Sciences, 2006
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The Molecular Mechanism of Chronic High-Dose Corticosterone-Induced Aggravation of Cognitive Impairment in APP/PS1 Transgenic Mice
long cao
Frontiers in Molecular Neuroscience
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Glucocorticoids and the regulation of memory in health and disease
Benno Roozendaal
Frontiers in Neuroendocrinology, 2009
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Glucocorticoid-Dependent Hippocampal Transcriptome in Male Rats: Pathway-Specific Alterations With Aging
Inga Kadish
Endocrinology, 2013
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Decrements in Nuclear Glucocorticoid Receptor (GR) Protein Levels and DNA Binding in Aged Rat Hippocampus
Erin Murphy
Endocrinology, 2002
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Amygdaloid Nuclei Lesions Differentially Affect Glucocorticoid-Induced Memory Enhancement in an Inhibitory Avoidance Task
Benno Roozendaal
Neurobiology of Learning and Memory, 1996
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Hippocampal glucocorticoid target genes associated with enhancement of memory consolidation
Patrizia Campolongo
European Journal of Neuroscience, 2021
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Regulation of Hippocampal Glucocorticoid Receptor Gene Transcription and Protein Expression In Vivo
robert spencer
1998
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Glucocorticoids may initiate Alzheimer’s disease: A Potential therapeutic role for mifepristone (RU486
Vikas Dhikav
Medical Hypotheses, 2007
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