Novel single-chain antibodies against highly conserved epitopes in the hemagglutinin of influenza A viruses: Promising agents for universal therapies (original) (raw)

An analysis of the properties of monoclonal antibodies directed to epitopes on influenza virus hemagglutinin

Lorena Brown

Archives of Virology, 1990

View PDFchevron_right

Characterization of mAb6-9-1 monoclonal antibody against hemagglutinin of avian influenza virus H5N1 and its engineered derivative, single-chain variable fragment antibody

Barbara Kalenik

Acta Biochimica Polonica, 2016

View PDFchevron_right

Isolation of cross-reactive, subtype-specific monoclonal antibodies against influenza virus HA1 and HA2 hemagglutinin subunits

José Melero, Nieves Villanueva

Archives of Virology, 1987

View PDFchevron_right

Conservation of epitopes recognized by monoclonal antibodies against the separated subunits of influenza hemagglutinin among type A viruses of the same and different subtypes

José Melero

Archives of Virology, 1991

View PDFchevron_right

A monoclonal antibody recognizes a highly conserved neutralizing epitope on hemagglutinin of H6N1 avian influenza virus

Jie-Long He

Veterinary microbiology, 2014

View PDFchevron_right

A Neutralizing Antibody Selected from Plasma Cells That Binds to Group 1 and Group 2 Influenza A Hemagglutinins

Davide Corti

Science, 2011

View PDFchevron_right

Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin

Emmanuel Walter

Proceedings of the National Academy of Sciences of the United States of America, 2011

View PDFchevron_right

An immuno-assay to quantify influenza virus hemagglutinin with correctly folded stalk domains in vaccine preparations

Weina Sun

PLOS ONE

View PDFchevron_right

Human single-chain antibodies that neutralize homologous and heterologous strains and clades of influenza A virus subtype H5N1

Kanyarat Thueng-In

Antiviral therapy, 2009

View PDFchevron_right

A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA

Thomas Voss

Nature communications, 2018

View PDFchevron_right

Differential neutralization efficiency of hemagglutinin epitopes, antibody interference, and the design of influenza vaccines

Simon Levin

Proceedings of the National Academy of Sciences, 2009

View PDFchevron_right

Human monoclonal antibodies derived from a patient infected with 2009 pandemic influenza A virus broadly cross-neutralize group 1 influenza viruses

Madiha S Ibrahim

Biochemical and Biophysical Research Communications, 2014

View PDFchevron_right

A Highly Potent and Broadly Neutralizing H1 Influenza-Specific Human Monoclonal Antibody

Sandra Ortega

Scientific reports, 2018

View PDFchevron_right

Generation of monoclonal pan-hemagglutinin antibodies for the quantification of multiple strains of influenza

Amine Kamen

PloS one, 2017

View PDFchevron_right

Study of immunogenicity of recombinant proteins based on hemagglutinin and neuraminidase conservative epitopes of influenza A virus

Ilya Dukhovlinov

2013

View PDFchevron_right

Cross-reactive single-domain antibodies to hemagglutinin stem region protect mice from group 1 influenza A virus infection

Dmitry Shcheblyakov

View PDFchevron_right

Epitope mapping of the hemagglutinin molecule of A/(H1N1)pdm09 influenza virus by using monoclonal antibody escape mutants

Katsumi Mizuta

Journal of virology, 2014

View PDFchevron_right

CONSTRUCTION AND EXPRESSION OF H5N1 INFLUENZA VIRUS HEMAGGLUTININ-SPECIFIC scFv-Fc MONOCLONAL ANTIBODIES IN HEK293T CELLS

Chonlatip Pipattanaboon

The Southeast Asian journal of tropical medicine and public health, 2017

View PDFchevron_right

Monoclonal antibodies targeting the synthetic peptide corresponding to the polybasic cleavage site on H5N1 influenza hemagglutinin

Alice Yu

Journal of Biomedical Science, 2012

View PDFchevron_right

A Human Antibody Recognizing a Conserved Epitope of H5 Hemagglutinin Broadly Neutralizes Highly Pathogenic Avian Influenza H5N1 Viruses

Lesley Calder

Journal of Virology, 2012

View PDFchevron_right

Neutralizing and protective epitopes of the 2009 pandemic influenza H1N1 hemagglutinin

Jackeline Stefany Reyes Soto

Influenza and Other Respiratory Viruses, 2012

View PDFchevron_right

Native Human Monoclonal Antibodies with Potent Cross-Lineage Neutralization of Influenza B Viruses

Ralph Tripp

Antimicrobial Agents and Chemotherapy, 2018

View PDFchevron_right

Antibodies elicited by influenza virus hemagglutinin fail to bind to synthetic peptides representing putative antigenic sites

Geoffrey Tregear

Molecular Immunology, 1985

View PDFchevron_right

Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody

Jack Ferdman

Proceedings of the National Academy of Sciences of the United States of America, 2017

View PDFchevron_right

Characterization of a broadly neutralizing monoclonal antibody that targets the fusion domain of group 2 influenza A virus hemagglutinin

ANDREW WARD

Journal of virology, 2014

View PDFchevron_right

Molecular Signatures of Hemagglutinin Stem-Directed Heterosubtypic Human Neutralizing Antibodies against Influenza A Viruses

Amr Fahmy

PLoS Pathogens, 2014

View PDFchevron_right

Cloning, expression and purification of hemagglutinin conserved domain (HA2) of influenza A virus, to be used in broad-spectrum subunit vaccine cocktails

behrokh farahmand

Vaccine Research, 2016

View PDFchevron_right

The breadth of cross sub-type neutralisation activity of a single domain antibody to influenza hemagglutinin can be increased by antibody valency

Simon Hufton

PloS one, 2014

View PDFchevron_right

Immunity and protection against influenza virus by synthetic peptide corresponding to antigenic sites of hemagglutinin

M. Shapira

Proceedings of the National Academy of Sciences, 1984

View PDFchevron_right

A Human Monoclonal Antibody with Neutralizing Activity against Highly Divergent Influenza Subtypes

Nicola Clementi, Larisa Gubareva

PLoS ONE, 2011

View PDFchevron_right

Quantitative Analyses of all Influenza Type A Viral Hemagglutinins and Neuraminidases using Universal Antibodies in Simple Slot Blot Assays

C. Gravel

Journal of Visualized Experiments, 2011

View PDFchevron_right