Green Approach Towards the Synthesis of 1-PHENYL Naphthalene Lignan and Their Derivatives (original) (raw)

2016

Abstract

The use of green chemistry technique reduces the chemical waste and reaction time. Recently, it has been proved in several organic synthesis and chemical transformation. In present work, synthesis of 1-phenyl naphthalene fromβ-Benzoyl propionic acid, aryl aldehyde, acetic anhydride and pyridine was carried out and it was cyclised with PPA and sulphamic acid, by using microwave irradiation. It is a three step reaction. In first step synthesis of α-arylidineγ-phenyl δ,β-butenolide by perkin reaction, in second step synthesis of α-arylidine, β-BenzoylPropionic acid by cleavage using alcoholic sodium carbonate and In third step synthesis of 1-phenyl naphthalene by cyclisation using PPA , H 2 SO 4 , Sulphamic acid has been carried out. It has been observed that microwave irradiation method produces better yield and reduces the time period compared with conventional method. The structure of 1-phenyl naphthalene was confirmed by spectral and elemental analysis.

Dr. Rajdip Utane hasn't uploaded this paper.

Let Dr. Rajdip know you want this paper to be uploaded.

Ask for this paper to be uploaded.