Risk Factors Leading to Major Lower Limb Amputations in Diabetic Patients with Foot Ulcers (original) (raw)

Predictors of lower limb amputations in patients with diabetic foot ulcers presenting to a tertiary care hospital of Pakistan

JPMA. The Journal of the Pakistan Medical Association, 2021

OBJECTIVE To assess the risk factors for lower limb amputations in diabetic patients presenting with foot ulcers. Methods The analytical cross-sectional study was conducted at the Mayo Hospital, Lahore, Pakistan, from December 1, 2019, to May 31, 2020, and comprised patients of either gender having type 1 or type 2 diabetes and foot ulcers. The wounds were assessed according to Wagner wound staging and wound sepsis was evaluated in terms of local infection of the wound, leucocytosis and osteomyelitis of the bone. The glycaemic control of these patients was assessed on presentation by measuring glycated haemoglobin levels. Data was analysed using SPSS 26. RESULTS Of the 135 patients, 82(60.7%) were males and 53(39.2%) were females. Majority patients 59(43.7%) were aged 50-60 years. All 135(100%) patients underwent some type of amputation. Of all the amputations, 91(67.4%) were done in patients with poor glycaemic control on presentation, and 56(41.5%) in those with stage 4 wound. Loc...

A Comparative Study on Diabetic Foot Ulcers Leading to Amputations

Journal of Postgraduate Medical Institute, 2018

Objective: To determine and compare the frequency of foot ulcers leading to amputations in relation to gender, type and duration of diabetes. Methodology: A descriptive study conducted at three teaching hospitals of Peshawar, from November-2015 to February-2016. Data was collected using convenient sampling technique via semi structured questionnaire. Inclusion cri- teria were diabetic, non-smoker, having no visible deformity other than ulcer or amputation; while critically ill patients, children less than 13 years, gestation- al diabetics and who did not consent upon were excluded. One hundred and twelve diabetics (type 1 & type 2) were included in the study. The collected data were entered and analyzed in SPSS version 23. P values were computed and significance level was set at <0.05. Results: Mean age was 53.55 ±11.58 years. Twenty four males (60%) had foot ulcers and among them, 16 (40%) got their lower leg amputated, whereas 55.5% females had foot ulcers and 24 (33%) among th...

Risk Factors for Lower Extremity Amputation in Diabetic Foot Ulcer Patients: A Case-Control Study

JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga

Introduction: Diabetes mellitus is a metabolic syndrome that is marked by higher blood glucose. The uncontrolled high blood glucose can lead to complication, such as diabetic foot. Diabetic foot is the most reason why diabetic patients are hospitalized. Diabetic foot that cannot heal may lead to lower extremity amputation. The purpose of this study was to describe the risk factors of lower extremity amputation in diabetic foot ulcer patients.Methods: This study used a case-control study of diabetic foot patients in Dr. Soetomo General Hospital from January 2015 to December 2017. This study used the data from medical records in Inpatient Installation Department of Internal Medicine. Patients with diabetic foot ulcer and lower extremity amputation due to diabetes were included in this study. Incomplete medical records were excluded. Data of samples were divided to two groups, i.e. the amputation group and the non-amputation group with a ratio of 1:1. Risk factors of amputation that we...

Evaluation of risk factors for lower extremity amputation in diabetic foot ulcer: a hospital based observational study in Northern India

International Journal of Research in Medical Sciences

Background: The present prospective observational study was done to analyse the risk factors leading to minor or major lower extremity amputation (LEA) in diabetic patients.Methods: A 139 patients were divided into Group A (n=113) and Group B (n=26) who underwent minor and major LEA respectively.Results: Majority of the patients in group B were from rural and lower socioeconomic background. Duration of diabetes (p=0.017) and of DFU was significantly longer in group B (P <0.001) The pro-portion of patients with Wagner Grade 4 and 5 ulcer were significantly higher in group B than in group A (P <0.001) Wound infection and maggots were significantly higher in group B though polymicrobial infection was higher in group A. Biochemical investigations were abnormally altered but difference between two groups was not significant.Conclusions: Socioeconomic burden on the society due to LEA can be reduced by making diabetic patients aware of foot hygiene, regular medical check-up for co...

Risk Factors for Lower Extremity Amputation in Patients with Diabetic Foot Ulcers

Background: The number patients with diabetic foot ulcers presenting to surgery clinics has been increasing at an alarming rate. Diabetic foot ulcers are the most common cause for nontraumatic foot amputation. This study was undertaken to analyze both the risk factors for development of foot ulcers in diabetics and for lower extremity amputation (LEA) in patients with diabetic foot ulcers. Methods: A prospective analytical study that assessed the various risk factors associated with the development of foot ulcers in diabetics and that eventually lead to LEA in these patients. Univariate analysis and multivariate logistic regression (WALD‘s TEST) were used to assess statistical significance. Results: A total of 120 patients were included in the study, of which 53 underwent LEA. The incidence of foot ulcers was found to be higher in the following categories: males, 5th decade, associated hypertension, hyperlipidemia, and duration of diabetes more than 5 years. The significant risk fac...