The Pathogenetic Role of HLA-B27 (original) (raw)
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This paper explores the pathogenetic role of HLA-B27 in various autoimmune diseases, emphasizing its involvement in diseases such as ankylosing spondylitis and reactive arthritis. Through an examination of genetic, immunological, and clinical studies, it discusses the mechanisms by which HLA-B27 may contribute to disease susceptibility and severity. The findings suggest that HLA-B27 may not only serve as a genetic risk factor but also play a direct role in the inflammatory processes associated with these conditions.
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