Phytochemical investigation, anti-inflammatory, antipyretic and antinociceptive activities of Zanthoxylum armatum DC extracts-in vivo and in vitro experiments (original) (raw)
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Medicinal, pharmaceutical and pharmacological properties of Zanthoxylum armatum: A Review
Journal of Pharmacognosy and Phytochemistry, 2018
Zanthoxylum armatum DC is a sub deciduous aromatic, branched shrub, belongs to family Rutaceae. Its maximum length up to approximately 5 m with alternate imparipinnate leaves and flowers are small, pale yellow in colour. It is widely spread in the hot valleys of Himalayas from Jammu to Bhutan, Nepal and Pakistan. In India, the most part of Orissa and Andhra Pradesh is covered by Z. armatum plants. This plant is significantly used to cure stomachic, toothache, carminative, antiseptic and chest infections. This review has collecting information about its botanical position, morphology, phytochemical and pharmacological information on Z armatum. Various researchers have shown that Zanthoxylum armatum posseses valuable biological and pharmacological activities. A large number of phytochemical compounds such as alkaloid, tennins, amino acids, terpenoids, glycosides are present in the extract of the leaves of Zanthoxylum armatum. This review focuses on the detailed medicinal uses, phytoch...
Phytochemical and pharmacological profile of Zanthoxylum armatum DC. An overview
2011
Zanthoxylum armatum DC. (Family Rutaceace), also known as Toothache tree occupies an important place in the history of Indian system of medicines. It is used as carminative, stomachic and anthelmintic and in the treatment of toothache. It contains volatile oil with active constituents such as linalool, limonene and lignan. Various studies indicated that it possesses antilarvicidal, antifungal, hepatoprotective and allelopathic properties. This review focuses on the detailed phytochemical composition and medicinal uses along with pharmacological properties of different parts of Z. armatum.
Phytochemistry and pharmacological profile of Zanthoxylum armatum: an overview
2011
Several research publications are published on the medicinal plant Hyssopus officinalis L. But, the researchers find quite a difficulty to study all the publications in a short while. The present review was designed to compile and summarize all the published works on the medicinal plant H. officinalis L. traditionally used in several systems of medicine (1885-2018). It showed that the medicinal plant H. officinalis L. belonging to family Lamiaceae, is a very important culinary, medicinal and perennial plant wildly cultivated in Asia, Europe and America. It possesses numerous phytoconstituents including quercetin-7-O-β-D-apiofuranosyl-(1→2)-β-D-xylopyranoside and quercetin-7-O-β-Dapiofuranosyl-(1→2)-β-D-xylopyranoside-3'-O-β-D-glucopyranoside and possesses antioxidant, anticonvulsant, antifungal, antimicrobial, antihemolytic, antiulcer, antispasmodic and several other pharmacological activities. Its essential oil is widely being used in cosmetic, food and pharmaceutical industries worldwide. Its oil is used as an herbal medicine and very precious food additive. It is one main ingredient of the official formulation of Chartreuse. Za'atar is its well-known herbal formulation. It is a quite significant medicinal plant which can be utilized for the treatment of several diseases such as microbial infection, epilepsy, ulcer, and spasm.
Anti-Inflammatory Investigations of Extracts of Zanthoxylum rhetsa
2021
Zanthoxylum rhetsa has been consumed in the diet in northern Thailand and also used as a medicament in ancient scripture for arthropathies. Thus, this study aimed to evaluate the activity of various extracts from differential parts of Z. rhetsa via inhibition of inflammatory mediators (NO, TNF-α, and PGE2) in RAW264.7 macrophages. The chemical composition in active extracts was also analyzed by GC/MS. The parts of this plant studied were whole fruits (F), pericarp (P), and seed (O). The methods of extraction included maceration in hexane, 95% ethanol and 50% ethanol, boiling in water, and water distillation. The results demonstrated that the hexane and 95% ethanolic extract from pericarp (PH and P95) and seed essential oil (SO) were the most active extracts. PH and P95 gave the highest inhibition of NO production with IC50 as 11.99 ± 1.66 μg/ml and 15.33 ± 1.05 μg/ml, respectively, and they also showed the highest anti-inflammatory effect on TNF-α with IC50 as 36.08 ± 0.55 μg/ml and...
Pharmacognostical and phytochemical screening of leaf extract of Zanthoxylum armatum DC
2013
Zanthoxylum armatum DC belongs to family Rutaceae is a sub deciduous aromatic shrub or small tree up to 5 m high. Bark pale brown rough croky; leave alternate imparipinnate, flowers small pale yellow and bisexual. Tender shoots are eaten as vegetable, suitable with pork and considered a good vegetable by Mishings. It is presumed that cooking with pork deworms, specially tap worms, by this vegetable. The Photomicrographic evaluation revealed interesting microscopic characteristic. The transverse section of the midrib showed schizolysogenous cavity which is a characteristic of family Rutaceae. Double layer of palisade and presence of sclerenchyma around vascular bundle is distinct identification characteristic. Also add to this is the presence of rosette shaped calcium oxalate crystals and prismatic crystals which are clearly visible in the parenchyma around vascular bundle. The leaves have anisocytic stomata which are surrounded by 4-6 straight walled subsidiary cells. Phytochemical ...
Journal of medicinal plant research
This paper compile a review on pharmacological studies, phytochemical analysis and problem associated with Zanthoxylum armatum DC. The different plant parts like leaves, fruits, stem, bark, seeds and roots are used in indigenous medicine preparation against various diseases. It shows antioxidative, antitumor, antiinflammatory, analgesic, antimicrobial and insecticidal/larvicidal activity. For their bioactive principles extensive chemical analysis resulted in this specie. Due to significant medicinal properties and continuous increasing demand put this plant in endangered category (IUCN). This plant has effective phytomedicinal action.