HMGA1 is a novel downstream nuclear target of the insulin receptor signaling pathway (original) (raw)

Pseudogene-mediated posttranscriptional silencing of HMGA1 can result in insulin resistance and type 2 diabetes

Mirella Filocamo

Nature Communications, 2010

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Functional Variants of the HMGA1 Gene and Type 2 Diabetes Mellitus

Vincent Durlach

JAMA, 2011

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Low-Frequency Variants in HMGA1 Are Not Associated With Type 2 Diabetes Risk

Marlène Huyvaert, S. Gaget

Diabetes, 2012

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Insulin signal transduction through protein kinase cascades

Joseph Avruch

Insulin Action, 1998

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E4orf1 protein reduces the need for endogenous insulin

Vijay Hegde

Nutrition & Diabetes, 2019

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20-HETE interferes with insulin signaling and contributes to obesity-driven insulin resistance

sakib hossain

Prostaglandins & Other Lipid Mediators, 2021

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The Missing Link between HAART, Mitochondrial Damage and Insulin Resistance

NATESAN GNANASEKARAN

Biomedical and Pharmacology Journal, 2020

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A Variation in 3′ UTR of hPTP1B Increases Specific Gene Expression and Associates with Insulin Resistance

Peter Almgren

The American Journal of Human Genetics, 2002

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Elevated insulin receptor content in human breast cancer

Vincenzo Papa

Journal of Clinical Investigation, 1990

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Polymorphism of HMGA1 is associated with increased risk of type 2 diabetes among Chinese individuals

S. Tanyolac

Diabetologia, 2012

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HMGA1 protein expression in familial breast carcinoma patients

Mara Colombo

European Journal of Cancer, 2010

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Molecular mechanisms by which GLP-1 RA and DPP-4i induce insulin sensitivity

habib yaribeygi

Life Sciences, 2019

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Development of brain insulin receptors

William Lowe

International Journal of Biochemistry, 1988

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The regulatory role of insulin in energy metabolism and leukocyte functions

Olga Gary

Journal of Leukocyte Biology

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Growth Hormone, Interferon-γ, and Leukemia Inhibitory Factor Utilize Insulin Receptor Substrate-2 in Intracellular Signaling

Nils Billestrup

Journal of Biological Chemistry, 1996

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Independent tissue contributors to obesity-associated insulin resistance

Eugene Barrett

JCI Insight, 2017

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Thioredoxin-interacting protein regulates insulin transcription through microRNA-204

Junqin Chen

Nature Medicine, 2013

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The role of the insulin-like growth factor-1 system in breast cancer

Michael Koutsilieris

Molecular Cancer, 2015

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Association between IgH enhancer hs1.2 and type 1 diabetes

Pietro D'Addabbo

Acta Diabetologica, 2018

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The High Mobility Group A1 (HMGA1) Transcriptome in Cancer and Development

Michael Koo

Current Molecular Medicine, 2016

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High HMGA2 expression and high body mass index negatively affect the prognosis of patients with ovarian cancer

Alessandro Ottaiano

Journal of Cellular Physiology, 2013

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Insulin signaling and addiction

Malcolm Avison

Neuropharmacology, 2011

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The insulin receptor translocates to the nucleus to regulate cell proliferation in liver

Maria Rosa Amaya

Hepatology, 2013

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Cellular Actions of the Insulin-Like Growth Factor Binding Proteins

Adda Grimberg

Endocrine Reviews, 2002

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Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice

M. Fedele, Daniela Foti, Antonio Brunetti

Nature Medicine, 2005

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Insulin supplementation attenuates cancer-induced cardiomyopathy and slows tumor disease progression

Denise Hilfiker-kleiner

JCI Insight, 2017

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Glucose-Dependent Insulinotropic Polypeptide Is Expressed in Pancreatic Islet α-Cells and Promotes Insulin Secretion

Rennian Wang

Gastroenterology, 2010

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High-insulinogenic nutrition—an etiologic factor for obesity and the metabolic syndrome?

Wolfgang Kopp

Metabolism, 2003

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Insulin receptor : tyrosine kinase activity and insulin action

Robert Ballotti

Reproduction Nutrition Development, 1989

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Insulin Resistance in the Metabolic Syndrome

Undurti Das

Metabolic Basis of Obesity, 2010

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Insulin resistance in an energy-centered perspective

edwin mariman

Physiology & Behavior, 2008

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Insulin Gene Expression Is Regulated by DNA Methylation

ismail abdullah

PLoS ONE, 2009

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The Fascinating Interplay between Growth Hormone, Insulin-Like Growth Factor-1, and Insulin

Kirsten Berk

Endocrinology and Metabolism, 2024

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Daniel Porte Jr.: A Leader in Our Understanding of the Role of Defective Insulin Secretion and Action in Obesity and Type 2 Diabetes

Gerald Taborsky

Diabetes Care, 2020

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The role of insulin dissociation from its endosomal receptor in insulin degradation

Barry Posner

Molecular and Cellular Endocrinology, 2000

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