In Vitro Antioxidant and Anti-HIV Activity of Endophytic Coumarin from Crotalaria pallida Aiton (original) (raw)
Journal of Fundamental and Applied Sciences, 2018
Endophytic fungi that reside in plant tissues are a potential source of secondary metabolites with biological activities. In our study, we investigated the detection of the antioxidant activity of the crude fungal extract of the genera Cladosporium, Alternaria, Aspergillus and Penicillium: endophytic fungi isolated from the leaves of Peganum harmala harvested in Laghouat and extract of these same leaves. The extraction of these metabolites was carried out using ethyl acetate. The antioxidant activity of the latter was carried out by the DPPH test. Our tests reveal that the extracts studied have a low antioxidant activity. The inhibitory concentrations show a higher antioxidant effect for the Penicillium extract compared to the other extracts studied. The antioxidant molecules are related to the content of polyphenols. Penicillium extract has the highest polyphenol content. Our results confirm that endophytic fungi are a potential and limited source of natural antioxidant compounds, in the same way as plants.
2020
Description of the subject: current investigative work is focused on the search for new antioxidant molecules of natural origin, to counter the damage that oxidative stress can cause and to propose therapeutic alternatives. Objective: the objective of this study is to relate the traditional use of Myrtus communis L. and Rhamnus alaternus L. by the population of Boumerdes and their antioxidant activity. Methods: the demonstration of the antioxidant power of the two plants consists of a phytochemical screening allowing to have an idea on the presence or the absence of certain primary and secondary metabolites. The antioxidant activity is evaluated by the method of reduction of iron on the three acetone, methanolic and ethanolic extracts. Results: phytochemical screening reveals a wealth of both plants in polyphenols, glucosides, saponosides, reducing sugars and flavonoids with an absence of catechic tannins, anthocyanins, carotenoids, irridoids, proteins, sterols, polyterpenes, starch...
pranamonde.co.za
Essential oils are frequently used for flavour and fragrance in the perfume, pharmaceutical, cosmetic and food industries. The antibacterial activity of the essential oil of Origanum compactum was tested (in solid and liquid media) against 16 clinical isolates. This oil showed a higher antibacterial activity against strains resistant to antibiotics. Résumé : L'huile essentielle d'Origanum compactum est testée, en milieux solide et liquide, pour son activité antibactérienne contre 16 souches bactériennes isolées de malades souffrant pour la plupart d'infections urinaires. Cette huile a témoigné d'une forte action antibactérienne même vis à vis de souches multirésistantes aux antibiotiques.
The essentials oils of the leave of Ageratum conyzoïdes, Eucalyptus citriodora, Cymbopogon nardus and Clausena anisata extracted by internment to steam are tested on some bacterias. The oils of Clausena anisata have the better action again all the bacterias. The GC and GC-SM are used to identify the chemical component. The oil of Clausena anisata and Ageratum conyzoïdes contained much hydrocarbon compounds. The volatile oils of Eucalyptus citriodora and Cymbopogon nardus in oxygen compounds.
Chemical composition and antimicrobial activity of Croton urucurana Baillon (Euphorbiaceae)
Journal of Ethnopharmacology, 1997
In the methanolic extract of Croton urucurana Baillon (Euphorbiaceae) a number of known compounds, such as acetyl aleuritolic acid, stigmasterol, β-sitosterol, campesterol, β-sitosterol-O-glucoside, sonderianin, catechin and gallocatechin were isolated and identified by MS and NMR spectroscopy, HRGC and data from literature. The antibacterial activity of the aqueous–EtOH extract, some fractions of the methanolic extract and some of the isolated compounds,
International Journal of Innovation and Applied Studies, 2020
The essential oil of Mondia whitei dry roots (Hook, f.) Skeels, harvested at Kindamba, in the Pool Department, south of Congo Brazzaville was extracted by hydrodistillation with a yield of 0.50%. Gas chromatography (GC) and gas chromatography-mass spectrometry (GC / MS) were used to characterize the chemical profile of the gas chromatography, then it was subjected to physicochemical analyzes. The physical and chemical properties evaluated were the refractive index and the acid number. The values of the refractive index in ether and in acetone are respectively 1.3703 and 1.3713 that of the determined acid number is zero. Taking into account the high proportion of 2-hydroxy-4-methoxy-benzaldehyde (99.85%), this oil could be a source of production of 2-hydroxy-4-methoxy-benzaldehyde useful for agri-food needs and a formulation necessary for Pharmaceutical industry.
International Journal of Innovation and Applied Studies, 2018
The phytochemical investigation carried out on five medicinal plants of Ivory Coast, used in the traditional treatment of the tooth decay first focused on the research of their chemical composition. The latter has resulted in the demonstration of several biomolecules (sterols, flavonoids, tannins, etc.), which have signed a good antioxidant profile. In a second time, it was devoted to the quantification of certain phytophenols. The results of this work indicated variable and significant levels overall. The stems of Ximenia americana exhibited the best antioxidant activity, which activity is dependent on its total phenolic compound rich (8802.94 ± 298.54 μgEAG / g), total flavonoids (18.39 ± 0.87%) and condensed tannins (99,369 ± 1,485 μgECT / mg).
Activités antioxydante et antiplasmodiale d’extraits de Massularia acuminata (Rubiaceae)
L'utilisation de Massularia acuminata (MA) par les populations Nkundo en médecine traditionnelle à Lui-Kotale en R.D. Congo aussi bien que par les bonobos nous a amenés à des investigations pharmacognosiques et phytochimiques. Le screening phytochimique des extraits aqueux de fruits (AF) et EtOH 80% d'écorces de tronc (EE) de MA ont révélé la présence d'alcaloïdes, flavonoïdes, leucoanthocyanes, saponosides et tanins. Mais également la présence d'anthocyanes, oses et holosides, quinones, sucres réducteurs dans les extraits AF, et ceux d'EE de stérols et triterpènes. La meilleure activité antioxydante est obtenue avec les extraits d'EE (CI 50 = 27,45 ± 2,56 μg/ml), et la plus forte activité
International Journal of Biological and Chemical Sciences, 2023
Euphorbia heterophylla est une plante adventice dont les graines sont consommées par certains animaux. Afin de déterminer la valeur nutritionnelle de ces graines brutes pour une éventuelle valorisation, cette étude a été menée. L'analyse phytochimique des graines a été réalisée selon les méthodes officielles. L'acide cyanhydrique a été dosé avec une solution de nitrate d'argent (AgNO3 ; 0,02 N). Les acides gras ont été déterminés par chromatographie en phase gazeuse. Les polyphénols et les flavonoïdes totaux ont été quantifiés par spectrophotométrie pendant que le potentiel du pouvoir antioxydant a été évalué par piégeage du radical libre 2,2-diphényl-1-picrylhydrazyle. Il en résulte que les teneurs en acides gras polyinsaturés C18 : 2 n-6 et C18 : 3 n-3 étaient respectivement de 18 et 54% des acides gras totaux identifiés. La teneur en acide cyanhydrique était de 122,4±10,2 mg/kg. La quantification des polyphénols et des flavonoïdes totaux a donné respectivement 206 mg EQ/g d'extrait et 23 mg EAG/g d'extrait. La valeur moyenne de la concentration IC50 était de 60,84 µg/mL. Les principaux résultats révèlent que les graines de Euphorbia heterophylla possèdent une puissante activité antioxydante et qu'elles peuvent être utilisées comme source d'enrichissement des produits animaux et d'origine animale en acides gras oméga-3.