A REVIEW ON FLOATING DRUG DELIVERY SYSTEM (original) (raw)

Present review addresses about floating drug delivery system. Gastric emptying is a complex process and makes in vivo performance of the drug delivery systems uncertain. In order to avoid this variability, efforts have been made to increase the retention time of the drug-delivery systems for more than 12 hours. The floating or hydro dynamically controlled drug delivery systems are useful in such application. In this review, the current technological developments of FDDS includes future scope, applications are discussed. Key Words: Gastric residence time (GRT), Floating Drug Delivery system (FDDS), Mucous membrane, Muco-adhesive Polymers,Effervescent Systems, Approaches, Limitations, Applications.