On the wrong DNA track: Molecular mechanisms of repeat-mediated genome instability (original) (raw)

Precarious maintenance of simple DNA repeats in eukaryotes

Jane Kim

BioEssays : news and reviews in molecular, cellular and developmental biology, 2017

View PDFchevron_right

Trinucleotide repeat instability: a hairpin curve at the crossroads of replication, recombination, and repair

C. Freudenreich, B. Lenzmeier

Cytogenetic and Genome Research, 2003

View PDFchevron_right

Short Inverted Repeats Are Hotspots for Genetic Instability: Relevance to Cancer Genomes

Albino Bacolla

Cell Reports, 2015

View PDFchevron_right

Features of trinucleotide repeat instability in vivo

Cynthia McMurray

Cell Research, 2008

View PDFchevron_right

The balancing act of DNA repeat expansions

Jane Kim

Current Opinion in Genetics & Development, 2013

View PDFchevron_right

Effects of Replication and Transcription on DNA Structure-Related Genetic Instability

Karen Vasquez

Genes, 2017

View PDFchevron_right

Instability of CTG Repeats is Governed by the Position of a DNA Base Lesion through Base Excision Repair

yan lai

PLoS ONE, 2013

View PDFchevron_right

Inverted Low-Copy Repeats and Genome Instability-A Genome-Wide Analysis

Claudia Gonzaga-Jauregui

Human mutation, 2012

View PDFchevron_right

Triplet repeat DNA structures and human genetic disease: dynamic mutations from dynamic DNA

Luda Shlyakhtenko, Yuri Lyubchenko

Journal of Biosciences, 2002

View PDFchevron_right

Mechanism of Trinucleotide Repeats Instabilities: The Necessities

X Pan

View PDFchevron_right

Increased Negative Superhelical Density in Vivo Enhances the Genetic Instability of Triplet Repeat Sequences

Albino Bacolla

Journal of Biological Chemistry, 2005

View PDFchevron_right

Instability of repetitive DNA sequences: the role of replication in multiple mechanisms

S. Lovett

… Academy of Sciences of the United …, 2001

View PDFchevron_right

Mutations in Yeast Replication Proteins That Increase CAG/CTG Expansions Also Increase Repeat Fragility

C. Freudenreich

Molecular and Cellular Biology, 2003

View PDFchevron_right

Disruption of Mechanisms That Prevent Rereplication Triggers a DNA Damage Response

Vincent Archambault

Molecular and Cellular Biology, 2005

View PDFchevron_right

Inverted DNA repeats: a source of eukaryotic genomic instability

Natalya Degtyareva

Molecular and cellular biology, 1993

View PDFchevron_right

The complex pathology of trinucleotide repeats

ps reddy

Current Opinion in Cell Biology, 1997

View PDFchevron_right

CTG repeat instability and size variation timing in DNA repair-deficient mice

Albert Pastink

The EMBO Journal, 2003

View PDFchevron_right

Induction of instability of normal length trinucleotide repeats within human disease genes

Laura Fernàndez López

Journal of Medical Genetics, 2004

View PDFchevron_right

Stress-Induced Modulators of Repeat Instability and Genome Evolution

Natalie Fonville

Journal of Molecular Microbiology and Biotechnology, 2011

View PDFchevron_right

DNA secondary structure: A common and causative factor for expansion in human disease

Cynthia McMurray

Proceedings of the National Academy of Sciences, 1999

View PDFchevron_right

Replication-dependent instability at (CTG)•(CAG) repeat hairpins in human cells

Michael Leffak

Nature Chemical Biology, 2010

View PDFchevron_right

Mechanisms of transcriptional dysregulation in repeat expansion disorders

Ruth Luthi-Carter

Biochemical Society Transactions, 2014

View PDFchevron_right

Double-strand breaks associated with repetitive DNA can reshape the genome

Piotr Mieczkowski

Proceedings of the National Academy of Sciences, 2008

View PDFchevron_right

SRS2 and SGS1 prevent chromosomal breaks and stabilize triplet repeats by restraining recombination

Rodrigo Bermejo

Nature Structural & Molecular Biology, 2009

View PDFchevron_right

A new look at the challenging world of tandem repeats

Valerio Parisi

Medical Hypotheses, 2000

View PDFchevron_right

Evidence of cis-acting factors in replication-mediated trinucleotide repeat instability in primate cells

Christopher Pearson

Nature Genetics, 2002

View PDFchevron_right

Double-strand break repair can lead to high frequencies of deletions within short CAG/CTG trinucleotide repeats

James Haber

Molecular and General Genetics MGG, 1999

View PDFchevron_right

DNA Re-replication Is Susceptible to Nucleotide Level Mutagenesis

Duyen Bui

Genetics

View PDFchevron_right

DNA repeats in the human genome

Goutam Gupta

Genetica, 1999

View PDFchevron_right

Triplet Repeat Instability and DNA Topology: An Expansion Model Based on Statistical Mechanics

Albino Bacolla

Journal of Biological Chemistry, 1997

View PDFchevron_right

Emerging roles of macrosatellite repeats in genome organization and disease development

Manuel Perucho

Epigenetics, 2017

View PDFchevron_right

Double-Strand Break Repair Pathways Protect against CAG/CTG Repeat Expansions, Contractions and Repeat-mediated Chromosomal Fragility in S. cerevisiae

Catherine Trujillo

View PDFchevron_right