Analytical response function for planar Ge detectors (original) (raw)
2016, Radiation Physics and Chemistry
Type 2 diabetes still remains a major challenge to human health management. Protein tyrosine phosphate 1B has been continuously explored for its therapeutic potential to treat type 2 diabetes as it is linked with negative regulation of insu signal transduction. QSAR studies were performed on derivatives of 2 and SVM aided linear and non-linear models were obtained which were further evaluated to identify descriptors revealing underlying structure-activity relationship. QSAR models were validated through a series of validation techniques like Y randomization and descriptor sensitivity in addition to internal validation parameters. Information content index (IC1) of neighbourhood symmetry of order-1 has bee activity relationship of 2-arylsulphonylaminobenzothiazoles derivatives. Geary auto polarizability are also actively correlated to biological respo
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