Molecular Evolution: Introduction (original) (raw)

Ecological and Evolutionary Genetics of Drosophila, 1990

Abstract

Variation in proteins and nucleic acid sequences can be used in a variety of ways to study evolutionary patterns and processes. In recent years, DNA sequences have largely superseded allozyme frequencies as the raw data for Drosophila molecular evolutionary biologists. DNA sequencing has been applied to three areas of investigation: the estimation of population genetic parameters, phylogenetic reconstructions, including estimates of rates of change in specific gene products, and the molecular basis of structural and regulatory gene mutations.

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