FRI0686 RELATIONSHIP Between Vitamin D Supplementation and Muscular Strength in Eldest Population. A Sistematic Review (original) (raw)

Background: Sarcopenia is the loss of skeletal muscle mass, strength and function that occurs as a consequence of aging. This condition result in physical disability, which limits the capacity to walk, increases the risk of falls and osteoporotic fractures. Several studies suggested an inverse relation between 25OHD serum levels, muscular strength and physical performance in the eldest. Objectives: To evaluate if vitamin D supplementation in patients > 50 years improves muscle mass, strength and performance in older patients. Methods: We performed a systematic review through Medline, Cochrane Library, and EMBASE. Inclusion criteria: 1) patients > 50 years old, 2) receiving treatment with vitamin D 3) muscle mass and muscle strength measurements 4) systematic reviews (SR) 5) randomized clinical trials (RCT) 6) Papers written in English or Spanish. Results: Five studies were included (4 SR and 1 RCT), n patients ranged from 121 to 5615. Patients mean age oscillated between 58-88 years, receiving variable vitamin D dose. Follow-up period fluctuated from 6 to 12 months.